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Sökning: onr:"swepub:oai:DiVA.org:liu-130322" > Effects of a Psycho...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005054naa a2200577 4500
001oai:DiVA.org:liu-130322
003SwePub
008160728s2016 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:133800054
024a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1303222 URI
024a https://doi.org/10.1159/0004453552 DOI
024a http://kipublications.ki.se/Default.aspx?queryparsed=id:1338000542 URI
040 a (SwePub)liud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Philipp Klein, Janu Medical University of Lubeck, Germany4 aut
2451 0a Effects of a Psychological Internet Intervention in the Treatment of Mild to Moderate Depressive Symptoms: Results of the EVIDENT Study, a Randomized Controlled Trial
264 c 2016-05-27
264 1b KARGER,c 2016
338 a print2 rdacarrier
500 a Funding Agencies|German Federal Ministry of Health [II A 5-2512 FSB 052]
520 a Background: Mild to moderate depressive symptoms are common but often remain unrecognized and treated inadequately. We hypothesized that an Internet intervention in addition to usual care is superior to care as usual alone (CAU) in the treatment of mild to moderate depressive symptoms in adults. Methods: This trial was controlled, randomized and assessor-blinded. Participants with mild to moderate depressive symptoms (Patient Health Questionnaire, PHQ-9, score 5-14) were recruited from clinical and non-clinical set-tings and randomized to either CAU or a 12-week Internet intervention (Deprexis) adjunctive to usual care. Outcomes were assessed at baseline, 3 months (post-assessment) and 6 months (follow-up). The primary outcome measure was self-rated depression severity (PHQ-9). The main analysis was based on the intention-to-treat principle and used linear mixed models. Results: A total of 1,013 participants were randomized. Changes in PHQ-9 from baseline differed significantly between groups (t(825) = 6.12, p amp;lt; 0.001 for the main effect of group). The post-assessment between-group effect size in favour of the intervention was d = 0.39 (95% CI: 0.13-0.64). It was stable at follow-up, with d = 0.32 (95% CI: 0.06-0.69). The rate of participants experiencing at least minimally clinically important PHQ-9 change at the post-assessment was higher in the intervention group (35.6 vs. 20.2%) with a number needed to treat of 7 (95% CI: 5-10). Conclusions: The Internet intervention examined in this trial was superior to CAU alone in reducing mild to moderate depressive symptoms. The magnitude of the effect is clinically important and has public health implications. (C) 2016 S. Karger AG, Basel
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Psykiatri0 (SwePub)302152 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Psychiatry0 (SwePub)302152 hsv//eng
653 a Internet intervention; Cognitive behaviour therapy; Depression; Randomized controlled trial
700a Berger, Thomasu University of Bern, Switzerland4 aut
700a Schroeder, Johannau University of Medical Centre Hamburg Eppendorf, Germany4 aut
700a Spaeth, Christinau Medical University of Lubeck, Germany4 aut
700a Meyer, Bjoernu GAIA AG, Germany; City University of London, England4 aut
700a Caspar, Franzu University of Bern, Switzerland4 aut
700a Lutz, Wolfgangu University of Trier, Germany4 aut
700a Arndt, Aliceu University of Trier, Germany4 aut
700a Greiner, Wolfgangu University of Bielefeld, Germany4 aut
700a Graefe, Violau University of Bielefeld, Germany4 aut
700a Hautzinger, Martinu University of Tubingen, Germany4 aut
700a Fuhr, Kristinau University of Tubingen, Germany4 aut
700a Rose, Matthiasu Charite, Germany; University of Massachusetts, MA 01605 USA4 aut
700a Nolte, Sandrau Charite, Germany; Deakin University, Australia4 aut
700a Loewe, Berndu University of Medical Centre Hamburg Eppendorf, Germany4 aut
700a Andersson, Gerhardu Karolinska Institutet,Linköpings universitet,Psykologi,Filosofiska fakulteten,Karolinska Institute, Sweden4 aut0 (Swepub:liu)geran87
700a Vettorazzi, Eiku University of Medical Centre Hamburg Eppendorf, Germany4 aut
700a Moritz, Steffenu University of Medical Centre Hamburg Eppendorf, Germany4 aut
700a Hohagen, Fritzu Medical University of Lubeck, Germany4 aut
710a Medical University of Lubeck, Germanyb University of Bern, Switzerland4 org
773t Psychotherapy and Psychosomaticsd : KARGERg 85:4, s. 218-228q 85:4<218-228x 0033-3190x 1423-0348
856u https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117387
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-130322
8564 8u https://doi.org/10.1159/000445355
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:133800054

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