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Can Removal of Midd...
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Lauri, K.Tallinn University of Technology, Estonia
(författare)
Can Removal of Middle Molecular Uremic Retention Solutes be Estimated by UV-absorbance Measurements in Spent Dialysate?
- Artikel/kapitelEngelska2015
Förlag, utgivningsår, omfång ...
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Cham :Springer,2015
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Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:liu-131740
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-131740URI
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https://doi.org/10.1007/978-3-319-19387-8_315DOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:kon swepub-publicationtype
Anmärkningar
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The objectives of this study were: (1) to compare removal of the middle molecular (MM) and small uremic retention solutes; (2) to investigate if MM removal can be assessed by UV-absorbance at the wavelength of 297 nm during various dialysis treatment modalities. Seven uremic patients, four females and three males, mean age 58.1 +/- 8.7 years, were included into the study during 28 chronic hemodialysis sessions. A parameter, reduction ratio (RR) in percentage, was calculated for a small uremic retention solute urea, for a MM retention solute beta2-microglobulin (B2M), and for UV-absorbance at the wavelength of 297 during different dialysis modalities: conventional hemodialysis (HD), high flux hemodialysis (HF-HD), and postdilutional online hemodiafiltration (HDF) with different parameter settings. Achieved results were compared regarding mean values and SD, and by systematic and standard errors (BIAS +/- SE). It was found that RR is similar for small and MM uremic retention solutes in case of dialysis modality with the highest convective transport, HDF (78.9 +/- 8.1% for urea and 78.1 +/- 6.8% for B2M, N=7). Moreover, RR of small uremic retention solutes can be estimated with sufficient accuracy by UV-absorbance at 297 nm in the spent dialysate for all modalities (BIAS +/- SE: 1.7 +/- 4.0%, N=28), and for MM uremic retention solutes only for HDF (BIAS +/- SE: 1.1 +/- 7.1%, N=7). The results should be confirmed by appropriate kinetic modeling in the next studies.
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Biuppslag (personer, institutioner, konferenser, titlar ...)
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Luman, M.Tallinn University of Technology, Estonia; North Estonian Medical Centre, Estonia
(författare)
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Holmar, J.Tallinn University of Technology, Estonia
(författare)
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Tomson, R.Tallinn University of Technology, Estonia
(författare)
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Kalle, S.Tallinn University of Technology, Estonia
(författare)
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Arund, J.Tallinn University of Technology, Estonia
(författare)
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Uhlin, FredrikLinköpings universitet,Institutionen för medicin och hälsa,Medicinska fakulteten,Region Östergötland, Njurmedicinska kliniken US,Tallinn University of Technology, Estonia(Swepub:liu)freuh89
(författare)
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Fridolin, I.Tallinn University of Technology, Estonia
(författare)
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Tallinn University of Technology, EstoniaTallinn University of Technology, Estonia; North Estonian Medical Centre, Estonia
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:WORLD CONGRESS ON MEDICAL PHYSICS AND BIOMEDICAL ENGINEERING, 2015, VOLS 1 AND 2Cham : Springer, s. 1297-130097833191938789783319193861
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