Sökning: onr:"swepub:oai:DiVA.org:liu-132217" > The Effect of Spati...
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000 | 04398naa a2200409 4500 | |
001 | oai:DiVA.org:liu-132217 | |
003 | SwePub | |
008 | 161021s2016 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1322172 URI |
024 | 7 | a https://doi.org/10.1371/journal.pone.01633162 DOI |
040 | a (SwePub)liu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Cibis, Merihu Linköpings universitet,Avdelningen för kardiovaskulär medicin,Medicinska fakulteten,Erasmus MC, Netherlands4 aut0 (Swepub:liu)merci42 |
245 | 1 0 | a The Effect of Spatial and Temporal Resolution of Cine Phase Contrast MRI on Wall Shear Stress and Oscillatory Shear Index Assessment |
264 | c 2016-09-26 | |
264 | 1 | b PUBLIC LIBRARY SCIENCE,c 2016 |
338 | a electronic2 rdacarrier | |
500 | a Funding Agencies|Dutch Technology Foundation STW [Carisma] [11629] | |
520 | a Introduction Wall shear stress (WSS) and oscillatory shear index (OSI) are associated with atherosclerotic disease. Both parameters are derived from blood velocities, which can be measured with phase-contrast MRI (PC-MRI). Limitations in spatiotemporal resolution of PC-MRI are known to affect these measurements. Our aim was to investigate the effect of spatiotemporal resolution using a carotid artery phantom. Methods A carotid artery phantom was connected to a flow set-up supplying pulsatile flow. MRI measurement planes were placed at the common carotid artery (CCA) and internal carotid artery (ICA). Two-dimensional PC-MRI measurements were performed with thirty different spatiotemporal resolution settings. The MRI flow measurement was validated with ultrasound probe measurements. Mean flow, peak flow, flow waveform, WSS and OSI were compared for these spatiotemporal resolutions using regression analysis. The slopes of the regression lines were reported in %/mm and %/100ms. The distribution of low and high WSS and OSI was compared between different spatiotemporal resolutions. Results The mean PC-MRI CCA flow (2.5 +/- 0.2mL/s) agreed with the ultrasound probe measurements (2.7 +/- 0.02mL/s). Mean flow (mL/s) depended only on spatial resolution (CCA:-13%/ mm, ICA:-49%/mm). Peak flow (mL/s) depended on both spatial (CCA:-13%/mm, ICA:17%/ mm) and temporal resolution (CCA:-19%/100ms, ICA:-24%/100ms). Mean WSS (Pa) was in inverse relationship only with spatial resolution (CCA:-19%/mm, ICA:-33%/mm). OSI was dependent on spatial resolution for CCA (-26%/mm) and temporal resolution for ICA (-16%/100ms). The regions of low and high WSS and OSI matched for most of the spatiotemporal resolutions (CCA: 30/30, ICA: 28/30 cases for WSS; CCA: 23/30, ICA: 29/30 cases for OSI). Conclusion We show that both mean flow and mean WSS are independent of temporal resolution. Peak flow and OSI are dependent on both spatial and temporal resolution. However, the magnitude of mean and peak flow, WSS and OSI, and the spatial distribution of OSI and WSS did not exhibit a strong dependency on spatiotemporal resolution. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Radiologi och bildbehandling0 (SwePub)302082 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Radiology, Nuclear Medicine and Medical Imaging0 (SwePub)302082 hsv//eng |
700 | 1 | a Potters, Wouter V.u Academic Medical Centre, Netherlands4 aut |
700 | 1 | a Gijsen, Frank J.u Erasmus MC, Netherlands4 aut |
700 | 1 | a Marquering, Henku Academic Medical Centre, Netherlands; AMC, Netherlands4 aut |
700 | 1 | a van Ooij, Pimu Academic Medical Centre, Netherlands4 aut |
700 | 1 | a I vanBave, Edu AMC, Netherlands4 aut |
700 | 1 | a Wentzel, Jolanda J.u Erasmus MC, Netherlands4 aut |
700 | 1 | a Nederveen, Aart J.u Academic Medical Centre, Netherlands4 aut |
710 | 2 | a Linköpings universitetb Avdelningen för kardiovaskulär medicin4 org |
773 | 0 | t PLOS ONEd : PUBLIC LIBRARY SCIENCEg 11:9, s. e0163316-q 11:9<e0163316-x 1932-6203 |
856 | 4 | u https://liu.diva-portal.org/smash/get/diva2:1040088/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 | u https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0163316&type=printable |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-132217 |
856 | 4 8 | u https://doi.org/10.1371/journal.pone.0163316 |
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