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Breast fat volume m...
Breast fat volume measurement in a wide-bore 3T MR: comparison of traditional mammographic density evaluation with MR density measurements using automatic segmentation.
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- Petridou, Elia (författare)
- Norfolk and Norwich University Hospital, UK
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- Kibiro, Minnie (författare)
- Norfolk and Norwich University Hospital, UK
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- Gladwell, Christina (författare)
- Norfolk and Norwich University Hospital, UK
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- Malcolm, Paul (författare)
- Norfolk and Norwich University Hospital, UK
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- Toms, Andoni (författare)
- Norfolk and Norwich University Hospital, UK
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- Juette, Arne (författare)
- Norfolk and Norwich University Hospital, UK
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- Borga, Magnus (författare)
- Linköpings universitet,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Medicinsk informatik,Tekniska fakulteten
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- Dahlqvist Leinhard, Olof, 1978- (författare)
- Linköpings universitet,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Avdelningen för radiologiska vetenskaper,Medicinska fakulteten,Region Östergötland, Radiofysikavdelningen US
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- Romu, Thobias (författare)
- Linköpings universitet,Medicinsk informatik,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Tekniska fakulteten
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- Kasmai, Bahman (författare)
- Norfolk and Norwich University Hospital, UK
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- Denton, Erika (författare)
- Norfolk and Norwich University Hospital, UK
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(creator_code:org_t)
- Saunders Elsevier, 2017
- 2017
- Engelska.
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Ingår i: Clinical Radiology. - : Saunders Elsevier. - 0009-9260 .- 1365-229X. ; 72:7, s. 565-572
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- AimTo compare magnetic resonance imaging (MRI) derived breast density measurements using automatic segmentation algorithms with radiologist estimations using the Breast Imaging Reporting and Data Systems (BI-RADS) density classification.Materials and Methods40 women undergoing mammography and dynamic breast MRI as part of their clinical management were recruited. Fat-water separated MR images derived from a 2-point Dixon technique, phase sensitive reconstruction and atlas based segmentation were obtained before and after intravenous contrast. Breast density was assessed using software from Advanced MR Analytics (AMRA), Linköping, Sweden with results compared to the widely used four-quartile quantitative BIRADS scale.ResultsThe proportion of glandular tissue of the breast on MRI was derived from the AMRA sequence. The mean unenhanced breast density was 0.31 ± 0.22 (mean ± SD) (left) and 0.29 ± 0.21 (right). Mean breast density on post-contrast images was 0.32 ± 0.19 (left) and 0.32 ± 0.2 (right). There was "almost perfect" correlation between pre and post-contrast breast density quantification: Spearman correlation rho=0.98 (95% confidence intervals (CI): 0.97-0.99) (left) and rho=0.99(CI: 0.98-0.99) (right). The 95% limits of agreement were -0.11-0.08 (left) and -0.08-0.03 (right).Interobserver reliability for BIRADS is "substantial": weighted Kappa k=0.8 (CI: 0.74- 0.87). The Spearman Correlation coefficient between BIRADs and MR breast density was rho=0.73 (CI: 0.60-0.82) (left) and rho=0.75 (CI: 0.63-0.83) (right) which is also "substantial".ConclusionThe AMRA sequence provides a fully automated, reproducible, objective assessment of fibroglandular breast tissue proportion that correlates well with mammographic assessment of breast density with the added advantage of avoidance of ionising radiation.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Medicinsk bildbehandling (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Medical Image Processing (hsv//eng)
Nyckelord
- MRI breast density
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Petridou, Elia
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Kibiro, Minnie
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Gladwell, Christ ...
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Malcolm, Paul
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Toms, Andoni
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Juette, Arne
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visa fler...
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Borga, Magnus
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Dahlqvist Leinha ...
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Romu, Thobias
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Kasmai, Bahman
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Denton, Erika
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Radiologi och bi ...
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- TEKNIK OCH TEKNOLOGIER
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TEKNIK OCH TEKNO ...
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och Medicinteknik
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och Medicinsk bildbe ...
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Clinical Radiolo ...
- Av lärosätet
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Linköpings universitet