Sökning: onr:"swepub:oai:DiVA.org:liu-134607" > Reversal learning s...
Fältnamn | Indikatorer | Metadata |
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000 | 03926naa a2200457 4500 | |
001 | oai:DiVA.org:liu-134607 | |
003 | SwePub | |
008 | 170221s2017 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1346072 URI |
024 | 7 | a https://doi.org/10.1111/ejn.134012 DOI |
040 | a (SwePub)liu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Böhme, Rebeccau Linköpings universitet,Centrum för social och affektiv neurovetenskap,Medicinska fakulteten,Charite, Germany4 aut0 (Swepub:liu)rebbo11 |
245 | 1 0 | a Reversal learning strategy in adolescence is associated with prefrontal cortex activation |
264 | c 2016-10-05 | |
264 | 1 | b WILEY-BLACKWELL,c 2017 |
338 | a print2 rdacarrier | |
500 | a Funding Agencies|Volkswagen Foundation [II/84 452]; Bundesministerium fur Bildung und Forschung (BMBF) [01ZX1311E]; Deutsche Forschungsgemeinschaft [GRK-1123, HE 2597/13-1] | |
520 | a Adolescence is a critical maturation period for human cognitive control and executive function. In this study, a large sample of adolescents (n=85) performed a reversal learning task during functional magnetic resonance imaging. We analyzed behavioral data using a reinforcement learning model to provide individually fitted parameters and imaging data with regard to reward prediction errors (PE). Following a model-based approach, we formed two groups depending on whether individuals tended to update expectations predominantly for the chosen stimulus or also for the unchosen one. These groups significantly differed in their problem behavior score obtained using the child behavior checklist (CBCL) and in a measure of their developmental stage. Imaging results showed that dorsolateral striatal areas covaried with PE. Participants who relied less on learning based on task structure showed less prefrontal activation compared with participants who relied more on task structure. An exploratory analysis revealed that PE-related activity was associated with pubertal development in prefrontal areas, insula and anterior cingulate. These findings support the hypothesis that the prefrontal cortex is implicated in mediating flexible goal-directed behavioral control. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Neurovetenskaper0 (SwePub)301052 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Neurosciences0 (SwePub)301052 hsv//eng |
653 | a adolescents; prediction error; prefrontal cortex; reversal learning | |
700 | 1 | a Lorenz, Robert C.u Charite, Germany; Max Planck Institute Human Dev, Germany4 aut |
700 | 1 | a Gleich, Tobiasu Charite, Germany; NeuroCure Excellence Cluster, Germany4 aut |
700 | 1 | a Romund, Lydiau Charite, Germany4 aut |
700 | 1 | a Pelz, Patriciau Charite, Germany4 aut |
700 | 1 | a Golde, Sabrinau Charite, Germany4 aut |
700 | 1 | a Flemming, Evau Charite, Germany4 aut |
700 | 1 | a Wold, Andrewu Linköpings universitet,Centrum för social och affektiv neurovetenskap,Medicinska fakulteten4 aut0 (Swepub:liu)andwo24 |
700 | 1 | a Deserno, Lorenzu Charite, Germany; Max Planck Institute Human Cognit and Brain Science, Germany; Otto von Guericke University, Germany4 aut |
700 | 1 | a Behr, Joachimu Charite, Germany; Charite, Germany; Medical School Brandenburg, Germany4 aut |
700 | 1 | a Raufelder, Dianau Freie University, Germany4 aut |
700 | 1 | a Heinz, Andreasu Charite, Germany4 aut |
700 | 1 | a Beck, Anneu Charite, Germany4 aut |
710 | 2 | a Linköpings universitetb Centrum för social och affektiv neurovetenskap4 org |
773 | 0 | t European Journal of Neuroscienced : WILEY-BLACKWELLg 45:1, s. 129-137q 45:1<129-137x 0953-816Xx 1460-9568 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-134607 |
856 | 4 8 | u https://doi.org/10.1111/ejn.13401 |
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