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Radiolabeled Nanopa...
Radiolabeled Nanoparticles for Cancer Diagnosis and Therapy
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- Koziorowski, Jacek (författare)
- Linköpings universitet,Institutionen för medicin och hälsa,Medicinska fakulteten,Region Östergötland, Radiofysikavdelningen US
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- Stanciu, Adina E. (författare)
- Institute Oncology Prof Dr Al Trestioreanu Bucharest, Romania
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- Gomez-Vallejo, Vanessa (författare)
- CIC biomaGUNE, Spain
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- Llop, Jordi (författare)
- CIC biomaGUNE, Spain
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(creator_code:org_t)
- BENTHAM SCIENCE PUBL LTD, 2017
- 2017
- Engelska.
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Ingår i: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY. - : BENTHAM SCIENCE PUBL LTD. - 1871-5206. ; 17:3, s. 333-354
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.2...
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Abstract
Ämnesord
Stäng
- Cancer remains as one of the major causes of death worldwide. The emergence of nanotechnology has opened new avenues for the development of nanoparticle (NP)-based diagnostic and therapeutic tools. NPs of different chemical composition, size, shape and surface decoration can be prepared using a wide variety of synthetic strategies. Subsequent radiolabelling with positron or gamma emitters results in potential diagnostic agents which may offer improved selectivity and/or specificity for the target organ or tissue, enabling the acquisition of images with higher signal-to-contrast ratio. Incorporation of alpha or beta emitters leads to therapeutic agents with application in the field of radiotherapy. Here, we first describe the different labeling strategies reported so far for the incorporation of radionuclides into NPs. Recent advances in the use of nanoparticulate constructs both in the diagnostic and therapeutic arenas are then discussed and examples of their application are briefly discussed.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- Radiolabelling; cancer diagnosis; therapy; radiometal; nanoparticles
Publikations- och innehållstyp
- ref (ämneskategori)
- for (ämneskategori)
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