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Early diabetic comp...
Early diabetic complications in a population of young patients with Type 1 diabetes mellitus despite intensive treatment
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- Nordwall, Maria (författare)
- Linköpings universitet,Pediatrik,Hälsouniversitetet
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- Hyllienmark, Lars (författare)
- Karolinska Institutet,Linköpings universitet,Klinisk Neurofysiologi,Hälsouniversitetet
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- Ludvigsson, Johnny (författare)
- Linköpings universitet,Pediatrik,Hälsouniversitetet
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(creator_code:org_t)
- Walter de Gruyter GmbH, 2006
- 2006
- Engelska.
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Ingår i: Journal of Pediatric Endocrinology & Metabolism. - : Walter de Gruyter GmbH. - 0334-018X .- 2191-0251. ; 19:1, s. 45-54
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Abstract
Ämnesord
Stäng
- Aim: To describe the prevalence of early complications in an unselected population of patients with type 1 diabetes mellitus (DM1) diagnosed in childhood with intensive insulin treatment from diagnosis.Methods: Eighty children and adolescents with DM1, age 7-22 years and DM1 duration >3 years, were studied. Neuropathy was defined as abnormal nerve conduction finding in ≥2 of 4 nerves (sural and peroneal nerves), nephropathy as albumin excretion rate ≥20 μg/min and retinopathy as all grades of retinal changes in fundus photographs.Results: The prevalence of neuropathy was 59%, of retinopathy 27% and of nephropathy 5% after 13 years DM1 duration. Mean (SD) long-term HbA1c was 8.4 (0.9)% (DCCT-corrected value).Conclusion: Even in a population with intensive insulin treatment from the beginning and fairly good metabolic control, the prevalence of subclinical neuropathy was high, while other diabetic complications were lower than usually reported.
Nyckelord
- type 1 diabetes mellitus ; diabetic nephropathy ; diabetic neuropathy ; diabetic retinopathy ; prevalence
- MEDICINE
- MEDICIN
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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