Sökning: onr:"swepub:oai:DiVA.org:liu-138923" > Prevalence of the m...
Fältnamn | Indikatorer | Metadata |
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000 | 04385naa a2200469 4500 | |
001 | oai:DiVA.org:liu-138923 | |
003 | SwePub | |
008 | 170627s2017 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1389232 URI |
024 | 7 | a https://doi.org/10.1016/j.ijantimicag.2016.12.0182 DOI |
040 | a (SwePub)liu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Bi, Zhenwangu Shandong Centre Disease Control and Prevent, Peoples R China4 aut |
245 | 1 0 | a Prevalence of the mcr-1 colistin resistance gene in extended-spectrum beta-lactamase-producing Escherichia coli from human faecal samples collected in 2012 in rural villages in Shandong Province, China |
264 | 1 | b ELSEVIER SCIENCE BV,c 2017 |
338 | a print2 rdacarrier | |
500 | a Funding Agencies|National Natural Science Foundation of China [71073098]; Swedish International Development Cooperation Agency; Swedish Institute for Communicable Disease Control [2010-001861] | |
520 | a Since its initial discovery in China in 2015, the plasmid-mediated colistin resistance gene mcr-1 has been reported in Escherichia coli isolated from clinical samples, animals and meat worldwide. In this study, 706 extended-spectrum beta-lactamase (ESBL)-producing E. coli from 411 persons were detected in a collection of faecal samples from 1000 rural residents in three counties in Shandong Province, China. These isolates were screened for mcr-1 and phenotypic colistin resistance. The gene was found in 3.5% of the isolates (from 4.9% of persons) from all three counties. All isolates with phenotypic colistin resistance carried mcr-1. These data indicate that commensal carriage of ESBL-producing E. coli with mcr-1 among persons in rural China was already present in 2012 and that mcr-1 was the most important colistin resistance mechanism. Interventions are necessary to minimise further dissemination of mcr-1, which would limit the future usefulness of colistin as a last-resort antibiotic. (C) 2017 Elsevier B.V. and International Society of Chemotherapy. All rights reserved. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Mikrobiologi inom det medicinska området0 (SwePub)301092 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Microbiology in the medical area0 (SwePub)301092 hsv//eng |
653 | a Drug resistance; Bacteria; Colistin; Escherichia coli; Rural China | |
700 | 1 | a Berglund, Björnu Linköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Medicinska fakulteten4 aut0 (Swepub:liu)bjobe50 |
700 | 1 | a Sun, Qiangu Shandong University, Peoples R China; Shandong University, Peoples R China4 aut |
700 | 1 | a Nilsson, Maudu Linköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Medicinska fakulteten4 aut0 (Swepub:liu)mauni03 |
700 | 1 | a Chen, Baoliu Shandong Centre Disease Control and Prevent, Peoples R China4 aut |
700 | 1 | a Tärnberg, Mariau Linköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Medicinska fakulteten4 aut0 (Swepub:liu)marta92 |
700 | 1 | a Ding, Liluu Shandong University, Peoples R China4 aut |
700 | 1 | a Stalsby Lundborg, Ceciliau Karolinska Institute, Sweden4 aut |
700 | 1 | a Bi, Zhenqiangu Shandong Centre Disease Control and Prevent, Peoples R China4 aut |
700 | 1 | a Tomson, Goranu Karolinska Institute, Sweden4 aut |
700 | 1 | a Yao, Jingjingu Shandong University, Peoples R China4 aut |
700 | 1 | a Gu, Zhanyingu Shandong University, Peoples R China4 aut |
700 | 1 | a Yin, Xiaou Jinan Central Hospital, Peoples R China4 aut |
700 | 1 | a Kou, Zengqiangu Shandong Centre Disease Control and Prevent, Peoples R China4 aut |
700 | 1 | a Nilsson, Lennart Eu Linköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Medicinska fakulteten4 aut0 (Swepub:liu)lenni43 |
710 | 2 | a Shandong Centre Disease Control and Prevent, Peoples R Chinab Avdelningen för mikrobiologi och molekylär medicin4 org |
773 | 0 | t International Journal of Antimicrobial Agentsd : ELSEVIER SCIENCE BVg 49:4, s. 493-497q 49:4<493-497x 0924-8579x 1872-7913 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-138923 |
856 | 4 8 | u https://doi.org/10.1016/j.ijantimicag.2016.12.018 |
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