Sökning: onr:"swepub:oai:DiVA.org:liu-140034" > Antiarrhythmic medi...
Fältnamn | Indikatorer | Metadata |
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000 | 04510naa a2200481 4500 | |
001 | oai:DiVA.org:liu-140034 | |
003 | SwePub | |
008 | 170829s2017 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1400342 URI |
024 | 7 | a https://doi.org/10.1016/j.ijcard.2017.05.0282 DOI |
040 | a (SwePub)liu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Alhede, Christinau Herlev Gentofte University Hospital, Denmark4 aut |
245 | 1 0 | a Antiarrhythmic medication is superior to catheter ablation in suppressing supraventricular ectopic complexes in patients with atrial fibrillation |
264 | 1 | b ELSEVIER IRELAND LTD,c 2017 |
338 | a print2 rdacarrier | |
500 | a Funding Agencies|Hans and Nora Buchards Foundation; Aage and Gerda Henschs Foundation; Jens Anker Andersens Foundation | |
520 | a Background: Supraventricular ectopic complexes (SVEC) originating in the pulmonary veins are known triggers of atrial fibrillation (AF) which led to the development of pulmonary vein isolation for AF. However, the long-term prevalence of SVEC after catheter ablation (CA) as compared to antiarrhythmic medication (AAD) is unknown. Our aims were to compare the prevalence of SVEC after AAD and CA and to estimate the association between baseline SVEC burden and AF burden during 24 months of follow-up. Methods: Patients with paroxysmal AF (N = 260) enrolled in the MANTRA PAF trial were treated with AAD (N = 132) or CA (N = 128). At baseline and 3, 6, 12, 18 and 24 months follow-up patients underwent 7-day Holter monitoring to assess SVEC and AF burden. We compared SVEC burden between treatments with Wilcoxon sum rank test. Results: Patients treated with AAD had significantly lower daily SVEC burden during follow-up as compared to CA (AAD: 19 [6-58] versus CA: 39 [14-125], p = 0.003). SVEC burden increased post-procedurally followed by a decrease after CA whereas after AAD SVEC burden decreased and stabilized after 3 months of follow-up. Patients with low SVEC burden had low AF burden after both treatments albeit this was more pronounced after CA at 24 months of follow-up. Conclusion: AAD was superior to CA in suppressing SVEC burden after treatment of paroxysmal AF. After CA SVEC burden increased immediately post-procedural followed by a decrease whereas after AAD an early decrease was observed. Lower SVEC burden was highly associated with lower AF burden during follow-up especially after CA. (C) 2017 Elsevier B.V. All rights reserved. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng |
653 | a Arrhythmia; Treatment; Ablation; Premature ectopic beats; Recurrence | |
700 | 1 | a Lauridsen, Trine K.u Herlev Gentofte University Hospital, Denmark4 aut |
700 | 1 | a Johannessen, Arneu Herlev Gentofte University Hospital, Denmark4 aut |
700 | 1 | a Dixen, Ulriku Hvidovre University Hospital, Denmark4 aut |
700 | 1 | a Jensen, Jan S.u Herlev Gentofte University Hospital, Denmark4 aut |
700 | 1 | a Raatikainen, Pekkau Helsinki University Hospital, Finland4 aut |
700 | 1 | a Hindricks, Gerhardu Leipzig University Hospital, Germany4 aut |
700 | 1 | a Walfridsson, Håkanu Linköpings universitet,Avdelningen för kardiovaskulär medicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US4 aut0 (Swepub:liu)hakwa83 |
700 | 1 | a Kongstad, Oleu Lund University Hospital, Sweden4 aut |
700 | 1 | a Pehrson, Steenu Rigshosp, Denmark4 aut |
700 | 1 | a Englund, Andersu Örebro University Hospital, Sweden4 aut |
700 | 1 | a Hartikainen, Juhau Kupio University Hospital, Finland4 aut |
700 | 1 | a Hansen, Peter S.u Varde Heart Centre, Denmark4 aut |
700 | 1 | a Nielsen, Jens C.u Aarhus University Hospital, Denmark4 aut |
700 | 1 | a Jons, Christianu Rigshosp, Denmark4 aut |
710 | 2 | a Herlev Gentofte University Hospital, Denmarkb Hvidovre University Hospital, Denmark4 org |
773 | 0 | t International Journal of Cardiologyd : ELSEVIER IRELAND LTDg 244, s. 186-191q 244<186-191x 0167-5273x 1874-1754 |
856 | 4 | u https://helda.helsinki.fi/bitstream/10138/297901/1/Antiarrhythmic_medication_is_superior.pdf |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-140034 |
856 | 4 8 | u https://doi.org/10.1016/j.ijcard.2017.05.028 |
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