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Effects of an Inter...
Effects of an Internet intervention (Deprexis) on severe depression symptoms : Randomized controlled trial
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- Meyer, Björn (författare)
- Research Department, Gaia, Hamburg, Germany Department of Psychology, City University London, United Kingdom
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- Bierbrodt, Julia (författare)
- Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
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- Schröder, Johanna (författare)
- Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
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- Berger, Thomas (författare)
- Department of Clinical Psychology and Psychotherapy, University of Bern, Switzerland
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- Beevers, Christopher G. (författare)
- Institute for Mental Health Research, University of Texas at Austin, Austin, USA
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- Weiss, Mario (författare)
- Research Department, Gaia, Hamburg, Germany
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- Jacob, Gitta (författare)
- Research Department, Gaia, Hamburg, Germany Department of Clinical Psychology and Psychotherapy, University of Freiburg, Germany
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- Späth, Christina (författare)
- Department of Psychiatry and Psychotherapy, University of Luebeck, Germany
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- Andersson, Gerhard, 1966- (författare)
- Linköpings universitet,Psykologi,Filosofiska fakulteten,Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institute, Stockholm, Sweden
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- Lutz, Wolfgang (författare)
- Department of Clinical Psychology and Psychotherapy, University of Trier, Germany
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- Hautzinger, Martin (författare)
- Department of Psychology, Clinical Psychology and Psychotherapy, Eberhard Karls University Tuebingen, Tuebingen, Germany
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- Löwe, Bernd (författare)
- Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Hamburg-Eppendorf, Germany Schön Klinik Hamburg Eilbek, Germany
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- Rose, Matthias (författare)
- Department of Psychosomatic Medicine, Charité University Medical Center, Berlin, Germany Department of Quantitative Health Sciences, University of Massachusetts Medical School, USA
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- Hohagen, Fritz (författare)
- Department of Psychiatry and Psychotherapy, University of Luebeck, Germany
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- Caspar, Franz (författare)
- Department of Clinical Psychology and Psychotherapy, University of Bern, Switzerland
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- Greiner, Wolfgang (författare)
- Department of Health Economics and Health Care Management, Bielefeld University, Bielefeld, Germany
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- Moritz, Steffen (författare)
- Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
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- Klein, Jan Philipp (författare)
- Department of Psychiatry and Psychotherapy, University of Luebeck, Germany
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(creator_code:org_t)
- Elsevier, 2015
- 2015
- Engelska.
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Ingår i: Internet Interventions. - : Elsevier. - 2214-7829. ; 2:1, s. 48-59
- Relaterad länk:
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
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- BackgroundStudies have shown that certain Internet interventions can help alleviate depression. However, many such interventions contain personal support elements, making it difficult to ascertain whether the program or the support drives the effects. Studies are needed to investigate whether Internet interventions contribute to symptom reduction even when they are delivered without personal support, and even among severely depressed individuals who often receive other forms of treatment.ObjectiveThis randomized controlled trial aimed to examine the effect of an Internet intervention that was deployed without personal support (“Deprexis”) among adults with initially severe depression symptoms.MethodsAdults recruited from a range of sources who had exceeded the threshold for severe depression (PHQ-9 ≥ 15) in a pre-screening assessment and met inclusion criteria were randomized (N = 163) to the intervention (3 months program access; n = 78) or care-as-usual/waitlist control (n = 85). A diagnostic screening interview was administered by telephone at baseline to all participants. Online assessments were administered at baseline, 3 months (post-treatment), and 6 months (follow-up). The main outcome was the Patient Health Questionnaire (PHQ-9) between baseline and post-treatment.ResultsEighty-two percent of randomized participants were reached for the post-treatment assessment. Results for the intention-to-treat (ITT) sample showed significant intervention effects on depression reduction between baseline and post-treatment (linear mixed model [MM], F1,155.6 = 9.00, p < .01, for the time by condition interaction), with a medium between-group effect size, Cohen's d = 0.57 (95% CI: 0.22–0.92). Group differences in depression severity at follow-up were marginally significant in the ITT sample, t (119) = 1.83, p = 0.07, and smaller than at post-treatment (PHQ-9, d = 0.33, 95% CI: − 0.03–0.69). The number needed to treat (NNT) at post-treatment was 5, with 38% of participants in the intervention group achieving response (at least 50% PHQ-9 symptom change, plus post-treatment score < 10), compared to 17% in the control group, p < 0.01. Effects on secondary outcomes, including anxiety, health-related quality of life, and somatic symptoms, were not significant, with the exception of significant effects on anxiety reduction in PP analyses. Early ratings of program helpfulness/alliance (after 3 weeks) predicted pre–post depression reduction, controlling for baseline severity and early symptom change.ConclusionsThese results replicate and extend previous findings by showing that Deprexis can facilitate symptomatic improvement over 3 months and, perhaps to a lesser degree, up until 6 months among adults with initially severe depression.
Ämnesord
- SAMHÄLLSVETENSKAP -- Psykologi -- Tillämpad psykologi (hsv//swe)
- SOCIAL SCIENCES -- Psychology -- Applied Psychology (hsv//eng)
Nyckelord
- Depression
- Internet-based treatment
- Randomized controlled trial
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Meyer, Björn
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Bierbrodt, Julia
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Schröder, Johann ...
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Berger, Thomas
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Beevers, Christo ...
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Weiss, Mario
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Jacob, Gitta
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Späth, Christina
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Andersson, Gerha ...
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Lutz, Wolfgang
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Hautzinger, Mart ...
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Löwe, Bernd
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Rose, Matthias
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Hohagen, Fritz
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Caspar, Franz
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Greiner, Wolfgan ...
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Moritz, Steffen
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Klein, Jan Phili ...
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