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Optical measurement...
Optical measurements during experimental stereotactic radiofrequency lesioning
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- Antonsson, Johan (författare)
- Linköpings universitet,Biomedicinsk instrumentteknik,Tekniska högskolan
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- Eriksson, Ola (författare)
- Linköpings universitet,Biomedicinsk instrumentteknik,Tekniska högskolan
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- Lundberg, Peter (författare)
- Linköpings universitet,Medicinsk radiofysik,Hälsouniversitetet
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- Wårdell, Karin (författare)
- Linköpings universitet,Biomedicinsk instrumentteknik,Tekniska högskolan,MINT
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(creator_code:org_t)
- 2006-08-03
- 2006
- Engelska.
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Ingår i: Stereotactic and Functional Neurosurgery. - : S. Karger. - 1011-6125 .- 1423-0372. ; 84:2-3, s. 118-124
- Relaterad länk:
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http://urn.kb.se/res...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- The aim of this study was to evaluate in vivo a laser Doppler measurement system in porcine brain tissue during thermal lesioning. A 2-mm monopolar radiofrequency lesioning electrode was equipped with optical fibers in order to monitor the lesioning procedure. Laser Doppler and backscattered light intensity signals were measured along the electrode trajectory and during bilateral lesioning in the central gray (70, 80 and 90°C, n = 14). The time course of the coagulation process could be followed by optical recordings. Two separate groups of tissue were identified from the intensity signals. The changes in the perfusion levels in both groups displayed significant changes (p < 0.05, n = 48) at all temperature settings, while backscattered light intensity was significant for only one group at the different temperatures (p < 0.05, n = 39). These results indicate that optical measurements correlate with lesion development in vivo. The study also indicates that it is possible to follow the lesioning process intra-operatively.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi -- Biomedicinsk laboratorievetenskap/teknologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology -- Biomedical Laboratory Science/Technology (hsv//eng)
Nyckelord
- Laser Doppler
- Radiofrequency lesioning
- Functional neurosurgery
- Brain electrodes
- TECHNOLOGY
- TEKNIKVETENSKAP
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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