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Simulation of refle...
Simulation of reflected light intensity changes during navigation and radio frequency lesioning in the brain
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- Johansson, Johannes D., 1977- (författare)
- Linköpings universitet,Tekniska högskolan,Biomedicinsk instrumentteknik,MINT
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- Fredriksson, Ingemar (författare)
- Linköpings universitet,Biomedicinsk instrumentteknik,Tekniska högskolan
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- Wårdell, Karin (författare)
- Linköpings universitet,Biomedicinsk instrumentteknik,Tekniska högskolan,MINT
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- Eriksson, Ola (författare)
- Linköpings universitet,Biomedicinsk instrumentteknik,Tekniska högskolan
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(creator_code:org_t)
- SPIE - International Society for Optical Engineering, 2009
- 2009
- Engelska.
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Ingår i: Journal of Biomedical Optics. - : SPIE - International Society for Optical Engineering. - 1083-3668 .- 1560-2281. ; 14:044040
- Relaterad länk:
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http://urn.kb.se/res...
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https://liu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- An electrode with adjacent optical fibers for measurements during navigation and radio frequency lesioning in the brain was modeled for Monte Carlo simulations of light transport in brain tissue. Relative reflected light intensity at 780 nm, I780, from this electrode and probes with identical fiber configuration were simulated using the intensity from native white matter as reference. Models were made of homogeneousnative and coagulated gray, thalamus, and white matter as well as blood. Dual layermodels, including models with a layer of cerebrospinal fluid between the fibers andthe brain tissue, were also made. Simulated I780 was 0.16 for gray matter, 0.67 forcoagulate gray matter, 0.36 for thalamus, 0.39 for coagulated thalamus, unity forwhite matter, 0.70 for coagulated white matter and 0.24 for blood. Thalamic matterhas also been found to reflect more light than gray matter and less than white matterin clinical studies. In conclusion the reflected light intensity can be used todifferentiate between gray and white matter during navigation. Furthermore,coagulation of light gray tissue, such as the thalamus, might be difficult to detectusing I780, but coagulation in darker gray tissue should result in a rapid increase of I780.
Ämnesord
- TEKNIK OCH TEKNOLOGIER -- Industriell bioteknik -- Bioteknisk apparatteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Industrial Biotechnology -- Bioengineering Equipment (hsv//eng)
Nyckelord
- Brain
- Monte Carlo simulations
- diffuse reflectance
- navigation
- radio-frequency lesioning
- MEDICINE
- MEDICIN
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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