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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 06268naa a2200433 4500 | |
| 001 | oai:DiVA.org:liu-163628 | |
| 003 | SwePub | |
| 008 | 200217s2020 | |||||||||||000 ||eng| | |
| 009 | oai:prod.swepub.kib.ki.se:142772314 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1636282 URI |
| 024 | 7 | a https://doi.org/10.1002/mp.139882 DOI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1427723142 URI |
| 040 | a (SwePub)liud (SwePub)ki | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Kaveckyte, Vaivau Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Karolinska Univ Hosp, Sweden4 aut0 (Swepub:liu)vaika19 |
| 245 | 1 0 | a Investigation of a synthetic diamond detector response in kilovoltage photon beams |
| 264 | c 2020-01-22 | |
| 264 | 1 | b Wiley-Blackwell Publishing Inc.c 2020 |
| 338 | a electronic2 rdacarrier | |
| 500 | a Funding Agencies|Swedish Cancer Society (Cancerfonden)Swedish Cancer Society [CAN 2015/618, CAN 2018/622] | |
| 520 | a Purpose An important characteristic of radiation dosimetry detectors is their energy response which consists of absorbed-dose and intrinsic energy responses. The former can be characterized using Monte Carlo (MC) simulations, whereas the latter (i.e., detector signal per absorbed dose to detector) is extracted from experimental data. Such a characterization is especially relevant when detectors are used in nonrelative measurements at a beam quality that differs from the calibration beam quality. Having in mind the possible application of synthetic diamond detectors (microDiamond PTW 60019, Freiburg, Germany) for nonrelative dosimetry of low-energy brachytherapy (BT) beams, we determined their intrinsic and absorbed-dose energy responses in 25-250 kV beams relative to a Co-60 beam, which is usually the reference beam quality for detector calibration in radiotherapy. Material and Methods Three microDiamond detectors and, for comparison, two silicon diodes (PTW 60017) were calibrated in terms of air-kerma free in air in six x-ray beam qualities (from 25 to 250 kV) and in terms of absorbed dose to water in a Co-60 beam at the national metrology laboratory in Sweden. The PENELOPE/penEasy MC radiation transport code was used to calculate the absorbed-dose energy response of the detectors (modeled based on blueprints) relative to air and water depending on calibration conditions. The MC results were used to extract the relative intrinsic energy response of the detectors from the overall energy response. Measurements using an independent setup with a single ophthalmic BEBIG I25.S16 I-125 BT seed (effective photon energy of 28 keV) were used as a qualitative check of the extracted intrinsic energy response correction factors. Additionally, the impact of the thickness of the active volume as well as the presence of extra-cameral components on the absorbed-dose energy response of a microDiamond detector was studied using MC simulations. Results The relative intrinsic energy response of the microDiamond detectors was higher by a factor of 2 in 25 and 50 kV beams compared to the Co-60 beam. The variation in the relative intrinsic energy response of silicon diodes was within 10% over the investigated photon energy range. The use of relative intrinsic energy response correction factors improved the agreement among the absorbed dose to water values determined using microDiamond detectors and silicon diodes, as well as with the TG-43 formalism-based calculations for the I-125 seed. MC study of microDiamond detector design features provided a possible explanation for inter-detector response variation at low-energy photon beams by differences in the effective thickness of the active volume. Conclusions MicroDiamond detectors had a non-negligible variation in the relative intrinsic energy response (factor of 2) which was comparable to that in the absorbed-dose energy response relative to water at low-energy photon beams. Silicon diodes, in contrast, had an absorbed-dose energy dependence on photon energy that varied by a factor of 6, whereas the intrinsic energy dependence on beam quality was within 10%. It is important to decouple these two responses for a full characterization of detector energy response especially when the user and reference beam qualities differ significantly, and MC alone is not enough. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Radiologi och bildbehandling0 (SwePub)302082 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Radiology, Nuclear Medicine and Medical Imaging0 (SwePub)302082 hsv//eng |
| 653 | a energy response; kilovoltage photon beams; synthetic diamond detector | |
| 700 | 1 | a Persson, Lindau Swedish Radiat Safety Author, Sweden4 aut |
| 700 | 1 | a Malusek, Alexandru Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Medicinsk strålningsfysik4 aut0 (Swepub:liu)alema80 |
| 700 | 1 | a Benmakhlouf, Hamzau Karolinska Univ Hosp, Sweden4 aut |
| 700 | 1 | a Alm Carlsson, Gudrunu Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Medicinsk strålningsfysik4 aut0 (Swepub:liu)gudal03 |
| 700 | 1 | a Carlsson Tedgren, Åsau Karolinska Institutet,Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Medicinsk strålningsfysik,Karolinska Univ Hosp, Sweden4 aut0 (Swepub:liu)asaca90 |
| 710 | 2 | a Linköpings universitetb Avdelningen för diagnostik och specialistmedicin4 org |
| 773 | 0 | t Medical physics (Lancaster)d : Wiley-Blackwell Publishing Inc.g 47:3, s. 1268-1279q 47:3<1268-1279x 0094-2405x 2473-4209 |
| 856 | 4 | u https://liu.diva-portal.org/smash/get/diva2:1393853/FULLTEXT01.pdfx primaryx Raw objecty fulltext:postprint |
| 856 | 4 | u http://liu.diva-portal.org/smash/get/diva2:1393853/FULLTEXT01 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-163628 |
| 856 | 4 8 | u https://doi.org/10.1002/mp.13988 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:142772314 |
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