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The histopathologic...
The histopathological diagnosis of atypical meningioma: glass slide versus whole slide imaging for grading assessment
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- Ammendola, Serena (författare)
- Univ Verona, Italy
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- Bariani, Elena (författare)
- Univ Verona, Italy
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- Eccher, Albino (författare)
- Univ & Hosp Trust Verona, Italy
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- Capitanio, Arrigo (författare)
- Linköpings universitet,Avdelningen för neurobiologi,Medicinska fakulteten,Region Östergötland, Klinisk patologi
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- Ghimenton, Claudio (författare)
- Univ & Hosp Trust Verona, Italy
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- Pantanowitz, Liron (författare)
- Univ Michigan, MI 48109 USA
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- Parwani, Anil (författare)
- Ohio State Univ, OH 43210 USA
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- Girolami, Ilaria (författare)
- Cent Hosp Bolzano, Italy
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- Scarpa, Aldo (författare)
- Univ Verona, Italy; Univ & Hosp Trust Verona, Italy
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- Barresi, Valeria (författare)
- Univ Verona, Italy; Polyclin GB Rossi, Italy
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(creator_code:org_t)
- 2020-12-10
- 2021
- Engelska.
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Ingår i: Virchows Archiv. - : SPRINGER. - 0945-6317 .- 1432-2307. ; 478, s. 747-756
- Relaterad länk:
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https://liu.diva-por... (primary) (Raw object)
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https://link.springe...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Limited studies on whole slide imaging (WSI) in surgical neuropathology reported a perceived limitation in the recognition of mitoses. This study analyzed and compared the inter- and intra-observer concordance for atypical meningioma, using glass slides and WSI. Two neuropathologists and two residents assessed the histopathological features of 35 meningiomas-originally diagnosed as atypical-in a representative glass slide and corresponding WSI. For each histological parameter and final diagnosis, we calculated the inter- and intra-observer concordance in the two viewing modes and the predictive accuracy on recurrence. The concordance rates for atypical meningioma on glass slides and on WSI were 54% and 60% among four observers and 63% and 74% between two neuropathologists. The inter-observer agreement was higher using WSI than with glass slides for all parameters, with the exception of high mitotic index. For all histological features, we found median intra-observer concordance of >= 79% and similar predictive accuracy for recurrence between the two viewing modes. The higher concordance for atypical meningioma using WSI than with glass slides and the similar predictive accuracy for recurrence in the two modalities suggest that atypical meningioma may be safely diagnosed using WSI.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
Nyckelord
- Atypical meningioma; Whole slide imaging; Digital; Recurrence; Reproducibility
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Ammendola, Seren ...
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Bariani, Elena
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Eccher, Albino
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Capitanio, Arrig ...
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Ghimenton, Claud ...
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Pantanowitz, Lir ...
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visa fler...
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Parwani, Anil
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Girolami, Ilaria
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Scarpa, Aldo
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Barresi, Valeria
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Urologi och njur ...
- Artiklar i publikationen
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Virchows Archiv
- Av lärosätet
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Linköpings universitet