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Predictors of treat...
Predictors of treatment benefits after enhanced external counterpulsation in patients with refractory angina pectoris
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- Wu, Eline (författare)
- Jönköping University,HHJ. ADULT,Jonkoping Univ, Sweden; Karolinska Univ Hosp, Sweden
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- Mårtensson, Jan, 1966- (författare)
- Jönköping University,HHJ, Avdelningen för omvårdnad,HHJ. ADULT,Jonkoping Univ, Sweden
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- Desta, Liyew (författare)
- Karolinska Institutet
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- Broström, Anders (författare)
- Jönköping University,HHJ, Avdelningen för omvårdnad,HHJ. ADULT,Region Östergötland, Neurofysiologiska kliniken US,Jonkoping Univ, Sweden
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Jönköping University HHJ ADULT (creator_code:org_t)
- 2021-01-05
- 2021
- Engelska.
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Ingår i: Clinical Cardiology. - : WILEY. - 0160-9289 .- 1932-8737. ; 44:2, s. 160-167
- Relaterad länk:
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https://liu.diva-por... (primary) (Raw object)
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https://onlinelibrar...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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http://kipublication...
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Abstract
Ämnesord
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- Background Enhanced external counterpulsation (EECP) is a noninvasive treatment that can decrease limiting symptoms in patients with refractory angina pectoris (RAP). Identifying responders to EECP is important as EECP is not widely available and relatively time intensive. Hypothesis The effect of EECP treatment on physical capacity in patients with RAP can be predicted from baseline patient characteristics and clinical factors. Methods This explorative study includes all patients from a cardiology clinic who had finished one EECP treatment and a 6 min walk test pre and post EECP. Clinical data, including Canadian Cardiovascular Society (CCS) classification and left ventricular ejection fraction (LVEF), were assessed before treatment. If patients increased their 6 min walking distance (6MWD) by 10% post EECP, they were considered responders. Results Of the 119 patients (men = 97, 40-91 years), 49 (41.2%) were responders. Multinomial regression analysis showed that functional status (i.e., CCS class >= 3) (OR 3.10, 95% CI 1.12-8.57), LVEF <50% (OR 2.82, 95% CI 1.02-7.80), and prior performed revascularization (i.e., <= 1 type of intervention) (OR 2.77, 95% CI 1.06-7.20) were predictors of response to EECP (p < .05, Accuracy 63.6%). Traditional risk factors (e.g., gender, smoking, and comorbidities) did not predict response. Conclusions EECP treatment should be considered preferentially for patients that have a greater functional impairment, evidence of systolic left ventricular dysfunction, and exposure to fewer types of revascularization, either PCI or CABG. Improvement in 6MWD post EECP could imply improvement in physical capacity, which is a likely contributor to improved well-being among patients with RAP.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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