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Sökning: onr:"swepub:oai:DiVA.org:liu-180911" > Management and outc...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00006371naa a2200781 4500
001oai:DiVA.org:liu-180911
003SwePub
008211109s2021 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:147952739
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1809112 URI
0247 a https://doi.org/10.1186/s12877-021-02476-42 DOI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1479527392 URI
040 a (SwePub)liud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Bruno, Raphael Romanou Heinrich Heine Univ Duesseldorf, Germany4 aut
2451 0a Management and outcomes in critically ill nonagenarian versus octogenarian patients
264 c 2021-10-19
264 1b BMC,c 2021
338 a electronic2 rdacarrier
500 a Funding Agencies|Western Health region in Norway; Projekt DEAL
520 a Background: Intensive care unit (ICU) patients age 90 years or older represent a growing subgroup and place a huge financial burden on health care resources despite the benefit being unclear. This leads to ethical problems. The present investigation assessed the differences in outcome between nonagenarian and octogenarian ICU patients. Methods: We included 7900 acutely admitted older critically ill patients from two large, multinational studies. The primary outcome was 30-day-mortality, and the secondary outcome was ICU-mortality. Baseline characteristics consisted of frailty assessed by the Clinical Frailty Scale (CFS), ICU-management, and outcomes were compared between octogenarian (80-89.9 years) and nonagenarian (>= 90 years) patients. We used multilevel logistic regression to evaluate differences between octogenarians and nonagenarians. Results: The nonagenarians were 10% of the entire cohort. They experienced a higher percentage of frailty (58% vs 42%; p < 0.001), but lower SOFA scores at admission (6 +/- 5 vs. 7 +/- 6; p < 0.001). ICU-management strategies were different. Octogenarians required higher rates of organ support and nonagenarians received higher rates of life-sustaining treatment limitations (40% vs. 33%; p < 0.001). ICU mortality was comparable (27% vs. 27%; p = 0.973) but a higher 30-day-mortality (45% vs. 40%; p = 0.029) was seen in the nonagenarians. After multivariable adjustment nonagenarians had no significantly increased risk for 30-day-mortality (aOR 1.25 (95% CI 0.90-1.74; p = 0.19)). Conclusion: After adjustment for confounders, nonagenarians demonstrated no higher 30-day mortality than octogenarian patients. In this study, being age 90 years or more is no particular risk factor for an adverse outcome. This should be considered- together with illness severity and pre-existing functional capacity - to effectively guide triage decisions.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Omvårdnad0 (SwePub)303052 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Nursing0 (SwePub)303052 hsv//eng
653 a Octogenarians; Nonagenarians; Frailty; Intensive care medicine; Outcome
7001 a Wernly, Bernhardu Paracelsus Med Univ, Austria; Karolinska Univ Hosp, Sweden4 aut
7001 a Kelm, Malteu Heinrich Heine Univ Duesseldorf, Germany; Cardiovasc Res Inst Dusseldorf, Germany4 aut
7001 a Boumendil, Arianeu St Hop Paris, France4 aut
7001 a Morandi, Alessandrou Dept Rehabil Hosp Ancelle Cremona, Italy; Geriatr Res Grp, Italy4 aut
7001 a Andersen, Finn H.u Alesund Hosp, Norway; NTNU, Norway4 aut
7001 a Artigas, Antoniou CIBERes Corporac Sanitaria Univ Parc Tau, Spain4 aut
7001 a Finazzi, Stefanou Ist Ric Farmacol Mario Negri IRCCS, Italy4 aut
7001 a Cecconi, Mauriziou Humanitas Univ, Italy4 aut
7001 a Christensen, Steffenu Aarhus Univ Hosp, Denmark4 aut
7001 a Faraldi, Loredanau Grande Osped Metropolitano Niguarda, Italy4 aut
7001 a Lichtenauer, Michaelu Paracelsus Med Univ, Austria4 aut
7001 a Muessig, Johanna M.u Heinrich Heine Univ Duesseldorf, Germany4 aut
7001 a Marsh, Brianu Mater Misericordiae Univ Hosp, Ireland4 aut
7001 a Moreno, Ruiu Univ Lisboa Cent, Portugal4 aut
7001 a Oeyen, Sandrau 1K12 Ghent Univ Hosp, Belgium4 aut
7001 a ohman, Christina Agvaldu Karolinska Univ Hosp, Sweden4 aut
7001 a Pinto, Bernardo Bollenu Geneva Univ Hospitals, Switzerland4 aut
7001 a Soliman, Ivo W.u Univ Utrecht, Netherlands4 aut
7001 a Szczeklik, Wojciechu Jagiellonian Univ, Poland4 aut
7001 a Valentin, Andreasu Kardinal Schwarzenberg Hosp, Austria4 aut
7001 a Watson, Ximenau St Georges Univ Hosp, England4 aut
7001 a Leaver, Susannahu Res Lead Critical Care Directorate St Georges Hos, England4 aut
7001 a Boulanger, Caroleu Royal Devon & Exeter NHS Fdn Trust, England4 aut
7001 a Walther, Stenu Region Östergötland, Thorax-kärlkliniken i Östergötland4 aut0 (Swepub:liu)stewa50
7001 a Schefold, Joerg C.u Univ Bern, Switzerland4 aut
7001 a Joannidis, Michaelu Med Univ Innsbruck, Austria4 aut
7001 a Nalapko, Yuriyu ICU, Ukraine4 aut
7001 a Elhadi, Muhammedu Alkhums Hosp, Libya4 aut
7001 a Fjolner, Jesperu Aarhus Univ Hosp, Denmark4 aut
7001 a Zafeiridis, Tilemachosu Gen Hosp Larissa, Greece4 aut
7001 a De Lange, Dylan W.u Univ Utrecht, Netherlands4 aut
7001 a Guidet, Bertrandu St Hop Paris, France; Sorbonne Univ, France; INSERM, France4 aut
7001 a Flaatten, Hansu Univ Bergen, Norway; Haukeland Hosp, Norway4 aut
7001 a Jung, Christianu Heinrich Heine Univ Duesseldorf, Germany4 aut
7102 a Heinrich Heine Univ Duesseldorf, Germanyb Paracelsus Med Univ, Austria; Karolinska Univ Hosp, Sweden4 org
7730 t BMC Geriatricsd : BMCg 21:1q 21:1x 1471-2318
8564 u https://liu.diva-portal.org/smash/get/diva2:1609703/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 u https://bmcgeriatr.biomedcentral.com/track/pdf/10.1186/s12877-021-02476-4
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-180911
8564 8u https://doi.org/10.1186/s12877-021-02476-4
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:147952739

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