Sökning: onr:"swepub:oai:DiVA.org:liu-182513" >
Neuropeptide Y as a...
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Zoccali, CarmineRenal Res Inst, NY 10027 USA; Osped Riuniti Reggio Calabria, Italy
(författare)
Neuropeptide Y as a risk factor for cardiorenal disease and cognitive dysfunction in chronic kidney disease : translational opportunities and challenges
- Artikel/kapitelEngelska2022
Förlag, utgivningsår, omfång ...
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2021-12-09
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Oxford University Press,2022
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electronicrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:liu-182513
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-182513URI
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https://doi.org/10.1093/ndt/gfab284DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:148538255URI
Kompletterande språkuppgifter
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Språk:engelska
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Sammanfattning på:engelska
Ingår i deldatabas
Klassifikation
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:for swepub-publicationtype
Anmärkningar
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Funding Agencies|COST Action CA19127-Cognitive Decline in Nephro-Neurology: European Cooperative Target (CONNECT)
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Neuropeptide Y (NPY) is a 36-amino-acid peptide member of a family also including peptide YY and pancreatic polypeptide, which are all ligands to Gi/Go coupled receptors. NPY regulates several fundamental biologic functions including appetite/satiety, sex and reproduction, learning and memory, cardiovascular and renal function and immune functions. The mesenteric circulation is a major source of NPY in the blood in man and this peptide is considered a key regulator of gut-brain cross talk. A progressive increase in circulating NPY accompanies the progression of chronic kidney disease (CKD) toward kidney failure and NPY robustly predicts cardiovascular events in this population. Furthermore, NPY is suspected as a possible player in accelerated cognitive function decline and dementia in patients with CKD and in dialysis patients. In theory, interfering with the NPY system has relevant potential for the treatment of diverse diseases from cardiovascular and renal diseases to diseases of the central nervous system. Pharmaceutical formulations for effective drug delivery and cost, as well as the complexity of diseases potentially addressable by NPY/NPY antagonists, have been a problem until now. This in part explains the slow progress of knowledge about the NPY system in the clinical arena. There is now renewed research interest in the NPY system in psychopharmacology and in pharmacology in general and new studies and a new breed of clinical trials may eventually bring the expected benefits in human health with drugs interfering with this system.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Ortiz, AlbertoUniv Leipzig, Germany
(författare)
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Blumbyte, Inga AruneLithuanian Univ Hlth Sci, Lithuania
(författare)
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Rudolf, SarinaUniv Leipzig, Germany
(författare)
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Beck-Sickinger, Annette G.Univ Leipzig, Germany
(författare)
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Malyszko, JolantaWarsaw Med Univ, Poland
(författare)
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Spasovski, GoceUniv Sta Cyril & Methodius, North Macedonia
(författare)
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Carriazo, SolUniv Leipzig, Germany
(författare)
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Viggiano, DavideUniv Campania Luigi Vanvitelli, Italy; Biogem Scarl, Italy
(författare)
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Kurganaite, JustinaLithuanian Univ Hlth Sci, Lithuania
(författare)
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Sarkeviciene, VaivaLithuanian Univ Hlth Sci, Lithuania
(författare)
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Rastenyte, DaivaLithuanian Univ Hlth Sci, Lithuania
(författare)
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Figurek, AndrejaUniv Zurich, Switzerland
(författare)
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Rroji, MeritaUniv Med Tirana, Albania
(författare)
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Mayer, ChristopherAustrian Inst Technol, Austria
(författare)
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Arici, MustaphaHacettepe Univ, Turkey
(författare)
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Martino, GianvitoIst Sci San Raffaele, Italy; Univ Vita Salute San Raffaele, Italy
(författare)
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Tedeschi, GioacchinoUniv Campania Luigi Vanvitelli, Italy; Univ Campania Luigi Vanvitelli, Italy
(författare)
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Bruchfeld, AnnetteKarolinska Institutet,Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Njurmedicinska kliniken US,CLINTEC Karolinska Inst, Sweden(Swepub:liu)anbru14
(författare)
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Spoto, BelindaCNR IFC, Italy
(författare)
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Rychlik, IvanCharles Univ Prague, Czech Republic; Fac Hosp Kralovske Vinohrady, Czech Republic
(författare)
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Wiecek, AndrzejMed Univ Silesia, Poland
(författare)
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Okusa, MarkUniv Virginia, VA USA; Univ Virginia, VA USA
(författare)
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Remuzzi, GiuseppeIst Ric Farmacol Mario Negri IRCCS, Italy
(författare)
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Mallamaci, FrancescaCNR IFC, Italy; Grande Osped Metropolitano, Italy
(författare)
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Renal Res Inst, NY 10027 USA; Osped Riuniti Reggio Calabria, ItalyUniv Leipzig, Germany
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Nephrology, Dialysis and Transplantation: Oxford University Press37, s. 14-230931-05091460-2385
Internetlänk
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Till lärosätets databas
- Av författaren/redakt...
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Zoccali, Carmine
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Ortiz, Alberto
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Blumbyte, Inga A ...
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Rudolf, Sarina
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Beck-Sickinger, ...
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Malyszko, Jolant ...
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visa fler...
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Spasovski, Goce
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Carriazo, Sol
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Viggiano, Davide
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Kurganaite, Just ...
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Sarkeviciene, Va ...
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Rastenyte, Daiva
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Figurek, Andreja
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Rroji, Merita
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Mayer, Christoph ...
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Arici, Mustapha
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Martino, Gianvit ...
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Tedeschi, Gioacc ...
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Bruchfeld, Annet ...
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Spoto, Belinda
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Rychlik, Ivan
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Wiecek, Andrzej
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Okusa, Mark
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Remuzzi, Giusepp ...
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Mallamaci, Franc ...
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Reumatologi och ...
- Artiklar i publikationen
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Nephrology, Dial ...
- Av lärosätet
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Linköpings universitet
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Karolinska Institutet