Sökning: onr:"swepub:oai:DiVA.org:liu-192184" >
A Soft and Stretcha...
A Soft and Stretchable Multielectrode Cuff for Selective Peripheral Nerve Stimulation
-
- Lienemann, Samuel (författare)
- Linköpings universitet,Laboratoriet för organisk elektronik,Tekniska fakulteten
-
- Donahue, Mary (författare)
- Linköpings universitet,Laboratoriet för organisk elektronik,Tekniska fakulteten
-
- Zötterman, Johan (författare)
- Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Hand- och plastikkirurgiska kliniken US
-
visa fler...
-
- Farnebo, Simon (författare)
- Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Hand- och plastikkirurgiska kliniken US
-
- Tybrandt, Klas (författare)
- Linköpings universitet,Laboratoriet för organisk elektronik,Tekniska fakulteten
-
visa färre...
-
(creator_code:org_t)
- 2023-01-31
- 2023
- Engelska.
-
Ingår i: Advanced Materials Technologies. - : WILEY. - 2365-709X. ; 8:6
- Relaterad länk:
-
https://liu.diva-por... (primary) (Raw object)
-
visa fler...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- Bioelectronic medicine can treat diseases and disorders in humans by electrically interfacing with peripheral nerves. Multielectrode cuffs can be used for selective stimulation of portions of the nerve, which is advantageous for treatment specificity. The biocompatibility and conformability of cuffs can be improved by reducing the mechanical mismatch between nerve tissue and cuffs, but selective stimulation of nerves has yet to be achieved with soft and stretchable cuff electrodes. Here, this paper reports the development of a soft and stretchable multielectrode cuff (sMEC) for selective nerve stimulation. The device is made of 50 mu m thick silicone with embedded gold nanowire conductors, which renders it functional at 50% strain, and provides superior conformability for wrapping nerves. By using different stimulation protocols, high functional selectivity is achieved with the sMECs eight stimulation electrodes in a porcine sciatic nerve model. Finite element modeling is used to predict the potential distribution within the nerve, which correlate well with the achieved stimulation results. Recent studies are showing that mechanical softness is of outermost importance for reducing foreign body response. It is therefore believed that the soft high-performance sMEC technology is ideal for future selective peripheral nerve interfaces for bioelectronic medicine.
Ämnesord
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Annan medicinteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Other Medical Engineering (hsv//eng)
Nyckelord
- cuff electrodes; gold nanowires; peripheral nerve stimulation; selective stimulation; stretchable electronics
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas