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Sökning: onr:"swepub:oai:DiVA.org:liu-202292" > Response strategies...

  • Li, ShuaiXiamen Univ, Peoples R China (författare)

Response strategies and biological applications of organic fluorescent thermometry: cell- and mitochondrion-level detection

  • Artikel/kapitelEngelska2024

Förlag, utgivningsår, omfång ...

  • 2024
  • ROYAL SOC CHEMISTRY,2024
  • printrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:liu-202292
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-202292URI
  • https://doi.org/10.1039/d4ay00117fDOI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:for swepub-publicationtype

Anmärkningar

  • Funding Agencies|National Natural Science Foundation of China [22077101]; CPSF [GZB20230379]; China Postdoctoral Science Foundation [2023M742919]; XMU; Fundamental Research Funds for the Central Universities; STINT Joint China-Sweden Mobility Project [CH2017-7243]; Carl Tryggers Stiftelse [CTS 23:2433]; Swedish Government Strategic Research Area in Materials Science on Advanced Functional Materials at Linkoeping University [2009 0097]
  • Temperature homeostasis is critical for cells to perform their physiological functions. Among the diverse methods for temperature detection, fluorescent temperature probes stand out as a proven and effective tool, especially for monitoring temperature in cells and suborganelles, with a specific emphasis on mitochondria. The utilization of these probes provides a new opportunity to enhance our understanding of the mechanisms and interconnections underlying various physiological activities related to temperature homeostasis. However, the complexity and variability of cells and suborganelles necessitate fluorescent temperature probes with high resolution and sensitivity. To meet the demanding requirements for intracellular/subcellular temperature detection, several strategies have been developed, offering a range of options to address this challenge. This review examines four fundamental temperature-response strategies employed by small molecule and polymer probes, including intramolecular rotation, polarity sensitivity, Forster resonance energy transfer, and structural changes. The primary emphasis was placed on elucidating molecular design and biological applications specific to each type of probe. Furthermore, this review provides an insightful discussion on factors that may affect fluorescent thermometry, providing valuable perspectives for future development in the field. Finally, the review concludes by presenting cutting-edge response strategies and research insights for mitigating biases in temperature sensing. In this review, we primarily summarized four temperature-response strategies. Then, we further analyzed the chemical modifications and biological applications of the probes. Finally, we have provided a prospective on the future development of probes.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Li, YaoxuanShanxi Med Univ, Peoples R China (författare)
  • Zhang, ShijiXiamen Univ, Peoples R China (författare)
  • Fang, HaixiaoXiamen Univ, Peoples R China; Future Display Inst Xiamen, Peoples R China (författare)
  • Huang, ZeXiamen Univ, Peoples R China (författare)
  • Zhang, DuotengXiamen Univ, Peoples R China (författare)
  • Ding, AixiangXiamen Univ, Peoples R China (författare)
  • Uvdal, KajsaLinköpings universitet,Molekylär ytfysik och nanovetenskap,Tekniska fakulteten(Swepub:liu)kajuv09 (författare)
  • Hu, Zhang-JunLinköpings universitet,Molekylär ytfysik och nanovetenskap,Tekniska fakulteten(Swepub:liu)zhahu14 (författare)
  • Huang, KaiFuture Display Inst Xiamen, Peoples R China (författare)
  • Li, LinXiamen Univ, Peoples R China; Future Display Inst Xiamen, Peoples R China (författare)
  • Xiamen Univ, Peoples R ChinaShanxi Med Univ, Peoples R China (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Analytical Methods: ROYAL SOC CHEMISTRY1759-96601759-9679

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