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Non-alcoholic fatty...
Non-alcoholic fatty liver disease and coexisting depression, anxiety and/or stress in adults: a systematic review and meta-analysis
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- Shea, Sue (författare)
- Univ Warwick, England; Univ Hosp Coventry & Warwickshire NHS Trust, England
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- Lionis, Christos (författare)
- Linköpings universitet,Avdelningen för prevention, rehabilitering och nära vård,Medicinska fakulteten,Univ Crete, Greece; Frederick Univ, Cyprus
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- Kite, Chris (författare)
- Univ Hosp Coventry & Warwickshire NHS Trust, England; Univ Wolverhampton, England; Univ Chester, England; Coventry Univ, England
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- Lagojda, Lukasz (författare)
- Univ Hosp Coventry & Warwickshire NHS Trust, England; Univ Hosp Coventry & Warwickshire NHS Trust, England
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- Uthman, Olalekan A. (författare)
- Univ Warwick, England
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- Dallaway, Alexander (författare)
- Univ Hosp Coventry & Warwickshire NHS Trust, England; Univ Wolverhampton, England
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- Atkinson, Lou (författare)
- Univ Warwick, England; Univ Hosp Coventry & Warwickshire NHS Trust, England; iPrescribe Exercise Digital Ltd EXI, England
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- Chaggar, Surinderjeet S. (författare)
- Sowe Valley Primary Care Network, England
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- Randeva, Harpal S. (författare)
- Univ Warwick, England; Univ Hosp Coventry & Warwickshire NHS Trust, England; Coventry Univ, England; Univ Hosp Coventry & Warwickshire NHS Trust, England
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- Kyrou, Ioannis (författare)
- Univ Warwick, England; Univ Hosp Coventry & Warwickshire NHS Trust, England; Coventry Univ, England; Univ Hosp Coventry & Warwickshire NHS Trust, England; Aston Univ, England; Univ Derby, England; Agr Univ Athens, Greece
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(creator_code:org_t)
- FRONTIERS MEDIA SA, 2024
- 2024
- Engelska.
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Ingår i: Frontiers in Endocrinology. - : FRONTIERS MEDIA SA. - 1664-2392. ; 15
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.3...
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Abstract
Ämnesord
Stäng
- Background Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver disease, affecting 25-30% of the general population globally. The condition is even more prevalent in individuals with obesity and is frequently linked to the metabolic syndrome. Given the known associations between the metabolic syndrome and common mental health issues, it is likely that such a relationship also exists between NAFLD and mental health problems. However, studies in this field remain limited. Accordingly, the aim of this systematic review and meta-analysis was to explore the prevalence of one or more common mental health conditions (i.e., depression, anxiety, and/or stress) in adults with NAFLD. Methods PubMed, EBSCOhost, ProQuest, Ovid, Web of Science, and Scopus were searched in order to identify studies reporting the prevalence of depression, anxiety, and/or stress among adults with NAFLD. A random-effects model was utilized to calculate the pooled prevalence and confidence intervals for depression, anxiety and stress. Results In total, 31 studies were eligible for inclusion, involving 2,126,593 adults with NAFLD. Meta-analyses yielded a pooled prevalence of 26.3% (95% CI: 19.2 to 34) for depression, 37.2% (95% CI: 21.6 to 54.3%) for anxiety, and 51.4% (95% CI: 5.5 to 95.8%) for stress among adults with NAFLD. Conclusion The present findings suggest a high prevalence of mental health morbidity among adults with NAFLD. Given the related public health impact, this finding should prompt further research to investigate such associations and elucidate potential associations between NAFLD and mental health morbidity, exploring potential shared underlying pathophysiologic mechanisms. Systematic review registration https://www.crd.york.ac.uk/prospero/, identifier CRD42021288934.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
Nyckelord
- non-alcoholic fatty liver disease; NAFLD; NASH; mental health; depression; anxiety; stress
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Shea, Sue
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Lionis, Christos
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Kite, Chris
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Lagojda, Lukasz
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Uthman, Olalekan ...
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Dallaway, Alexan ...
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Atkinson, Lou
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Chaggar, Surinde ...
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Randeva, Harpal ...
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Kyrou, Ioannis
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