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Developing chicken ...
Developing chicken oligodendrocytes express the type IV oligodendrocyte marker T4-O in situ, but not in vitro
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- Anderson, Emma S., 1975- (författare)
- Linköpings universitet,Cellbiologi,Hälsouniversitetet
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- Bjartmar, Carl (författare)
- Linköpings universitet,Cellbiologi,Hälsouniversitetet
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- Eriksson, Cecilia (författare)
- Linköpings universitet,Cellbiologi,Hälsouniversitetet
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- Westermark, Gunilla, 1958- (författare)
- Linköpings universitet,Cellbiologi,Hälsouniversitetet
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- Hildebrand, Claes, 1941- (författare)
- Linköpings universitet,Cellbiologi,Hälsouniversitetet
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(creator_code:org_t)
- 2000
- 2000
- Engelska.
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Ingår i: Neuroscience Letters. - 0304-3940 .- 1872-7972. ; 284:1-2, s. 21-24
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Accumulating data suggest that the oligodendrocyte population includes morphological and biochemical subtypes. We recently reported that a polyclonal antiserum against an unknown antigen, the T4-O molecule, labels a subpopulation of chicken oligodendrocytes, obviously representing the type IV variety of Del Rio Hortega. The present study examines the developmental expression of the T4-O molecule in situ and in vitro. The results show that T4-O immunoreactive cells first appear at E15 in the ventral funiculus. But, oligodendrocytes cultured in vitro with or without neurones do not develop a T4-O immunoreactivity. We conclude that oligodendrocytes in the spinal cord of chicken embryos first express the T4-O molecule some time after onset of myelination, and that the T4-O immunoreactive phenotype does not develop in vitro.
Nyckelord
- MEDICINE
- MEDICIN
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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