Sökning: onr:"swepub:oai:DiVA.org:liu-24873" >
Surgery for Crohn c...
Surgery for Crohn colitis over a twenty-eight-year period : fewer stomas and the replacement of total colectomy by segmental resection
-
- Andersson, Peter, 1957- (författare)
- Linköpings universitet,Kirurgi,Hälsouniversitetet
-
- Olaison, Gunnar, 1947- (författare)
- Linköpings universitet,Kirurgi,Hälsouniversitetet
-
- Bodemar, Göran, 1941- (författare)
- Linköpings universitet,Gastroenterologi och hepatologi,Hälsouniversitetet
-
visa fler...
-
- Nyström, Per-Olof, 1947- (författare)
- Linköpings universitet,Kirurgi,Hälsouniversitetet
-
- Sjödahl, Rune, 1938- (författare)
- Linköpings universitet,Kirurgi,Hälsouniversitetet
-
visa färre...
-
(creator_code:org_t)
- 2009-07-08
- 2002
- Engelska.
-
Ingår i: Scandinavian Journal of Gastroenterology. - : Informa UK Limited. - 0036-5521 .- 1502-7708. ; 37:1, s. 68-73
- Relaterad länk:
-
https://urn.kb.se/re...
-
visa fler...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- Background: This study describes how surgery for Crohn colitis developed between 1970 and 1997, towards the end of which period limited resection and medical maintenance treatment was introduced.Methods: A cohort of 211 patients with Crohn colitis (115 population-based), of which 84 had a primary colonic resection (42 population-based), was investigated regarding indication for surgery, the time from diagnosis to operation, type of primary colonic resection, risk for permanent stoma and medication over four 7-year periods.Results: Comparison of the periods 1970-90 and 1991-97 revealed that active disease as an indication for surgery decreased from 64% to 25% ( P < 0.01) while stricture as an indication increased from 9% to 50% ( P < 0.001). Median time from diagnosis to operation increased from 3.5 to 11.5 years ( P < 0.01). Proctocolectomy or colectomy fell from 68.8% to 10% of the primary resections, whereas segmental resection increased from 31.2% to 90%. At the end of the first 7-year period, 26% had medical maintenance treatment, steroids or azathioprine taken by 7%. Corresponding figures for the last period were 70% and 49%. Patients diagnosed during the last two time-periods had less risk for surgery ( P = 0.017), permanent stoma ( P < 0.01) and total colectomy ( P < 0.01). Findings were similar in the population-based cohort.Conclusions: Current management of Crohn colitis implies a longer period between diagnosis and surgery, a reduced risk for surgery and permanent stoma, and the replacement of total colectomy by segmental resection.
Nyckelord
- Colectomy
- Colitis
- Crohn Disease
- Population-BASED
- Stoma
- Surgery
- MEDICINE
- MEDICIN
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas