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Prevalence of coeli...
Prevalence of coeliac disease and relations to Helicobacter pylori infection and duodenitis in a Swedish adult population sample : A histomorphological and serological survey
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- Borch, Kurt, 1944- (författare)
- Östergötlands Läns Landsting,Linköpings universitet,Hälsouniversitetet,Kirurgi,GE: Gastrokir
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- Grodzinsky, Ewa, 1958- (författare)
- Östergötlands Läns Landsting,Linköpings universitet,Hälsouniversitetet,Klinisk immunologi,Klinisk immunologi och transfusionsmedicin
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- Petersson, Fredrik (författare)
- Linköpings universitet,Hälsouniversitetet,Kirurgi
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Jönsson, Kjell-Åke (författare)
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- Mårdh, Sven, 1947- (författare)
- Linköpings universitet,Hälsouniversitetet,Cellbiologi
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- Valdimarsson, Trausti (författare)
- Linköpings universitet,Hälsouniversitetet,Gastroenterologi och hepatologi
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(creator_code:org_t)
- Springer Science and Business Media LLC, 2000
- 2000
- Engelska.
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Ingår i: InflammoPharmacology. - : Springer Science and Business Media LLC. - 0925-4692 .- 1568-5608. ; 8:4, s. 341-350
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Aim: The aim of this study was to determine the prevalence of coeliac disease and its relation to duodenitis, H. pylori infection and gastritis in a sample of the adult general population. Methods: A Swedish population sample of 482 subjects (aged 35 to 85 years) were examined with gastro-duodenoscopy with multiple biopsies taken. Circulating antibodies to endomycium, gliadin, and H. pylori were also determined. Results: Based on histomorphological findings, coeliac disease was evident in 9 of 482 subjects giving a prevalence of 1.9 [1.0-4.0, 95% confidence interval] percent. The prevalence of gastritis with or without H. pylori infection did not differ between subjects with and without coeliac disease. Considering subjects without coeliac disease, there was no difference in the serum levels of gliadin antibodies between those with and without duodenitis. However, subjects with positive H. pylori status had significantly higher levels of gliadin antibodies than those with negative H. pylori status. Conclusions: This study confirms that there is a relatively high prevalence of undiagnosed coeliac disease in Swedish adults. There was no association between coeliac disease and H. pylori infection or gastritis, although serum gliadin antibody levels were slightly increased in subjects with positive H. pylori status.
Nyckelord
- MEDICINE
- MEDICIN
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- ref (ämneskategori)
- art (ämneskategori)
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