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Biochemical Mathema...
Biochemical Mathematical Modeling with Modelica and the BioChem Library
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- Fritzson, Peter (författare)
- Linköpings universitet,Institutionen för datavetenskap,PELAB
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Ulfhielm, Erik (författare)
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- Belic, Ales (författare)
- Faculty of Electrical Engineering, University of Ljubljana
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visa fler...
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- Fransson, Martin, 1978- (författare)
- Linköpings universitet,Institutionen för datavetenskap,PELAB
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- Green, Henrik, 1975- (författare)
- Hälsouniversitetet, Faculty of Health Sciences
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visa färre...
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(creator_code:org_t)
- 2007
- 2007
- Engelska.
- Relaterad länk:
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https://urn.kb.se/re...
Abstract
Ämnesord
Stäng
- Considering the large amounts of data that is nowadays produced in the biochemistry (functional genomics) it is difficult to extract the information from the measurements. There is currently also a great interest in the development of novel analytical technologies for rapid screening of disease symptoms in pharmaceutical and clinical ap-plications. Modeling and simulation can provide a useful help in understanding the rela-tions of the measured substances and to minimize the need for measurements. The Bio-Chem library presented here is the first free Modelica library available for mathematical modeling of biochemical processes. Three examples are shown to illustrate the library. First, a simple insulin model is presented. Then a simplified model of cholesterol to-gether with simulations are shown. Next, a simple drug model together with parameter estimation in NONMEN are presented. The BioChem library allows for fast and end-user friendly modeling of biomedical systems. The graphical user interface provides graphics similar to that used in the description of metabolic pathways in biochemistry.
Ämnesord
- NATURVETENSKAP -- Data- och informationsvetenskap -- Datavetenskap (hsv//swe)
- NATURAL SCIENCES -- Computer and Information Sciences -- Computer Sciences (hsv//eng)
Nyckelord
- cholesterol metabolic pathways
- feedback control
- functional ge
- Computer science
- Datavetenskap
Publikations- och innehållstyp
- ref (ämneskategori)
- kon (ämneskategori)