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mGluR-Mediated calc...
mGluR-Mediated calcium oscillations in the lamprey: a computational model
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- Hallén, Kristofer (författare)
- Linköpings universitet,Biologiska Beräkningar,Tekniska högskolan,Dept. of Physics/Msrmt. Technology, Linköping University
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- Huss, Mikael (författare)
- KTH,Numerisk analys och datalogi, NADA
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- Kettunen, Petronella (författare)
- Karolinska Institutet,Nobel Institute for Neurophysiology, Department of Neuroscience, Karolinska Institutet
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- El Manira, Abdeljabbar (författare)
- Karolinska Institutet,Nobel Institute for Neurophysiology, Department of Neuroscience, Karolinska Institutet
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- Kotaleski, Jeanette Hällgren (författare)
- KTH,Karolinska Institutet,Numerisk analys och datalogi, NADA
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(creator_code:org_t)
- AMSTERDAM : Elsevier BV, 2004
- 2004
- Engelska.
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Ingår i: Neurocomputing. - AMSTERDAM : Elsevier BV. - 0925-2312 .- 1872-8286. ; 58-60, s. 431-435, s. 431-435
- Relaterad länk:
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http://dx.doi.org/10...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Slow Ca2+ oscillations caused by release from intracellular stores have been observed in neurons in the lamprey spinal cord. These oscillations are triggered by activation of metabotropic glutamate receptors on the cell surface. The pathway leading from receptor activation to the inositol triphosphate-mediated release of Ca2+ from the endoplasmatic reticulum has been modelled in order to facilitate further understanding of the nature of these oscillations. The model generates Ca2+ oscillations with a frequency range of 0.01–0.09 Hz. A prediction of the model is that the frequency will increase with a stronger extracellular glutamate signal.
Ämnesord
- NATURVETENSKAP -- Data- och informationsvetenskap -- Datavetenskap (hsv//swe)
- NATURAL SCIENCES -- Computer and Information Sciences -- Computer Sciences (hsv//eng)
Nyckelord
- Calcium oscillations
- Lamprey
- mGluR5
- Spinal cord
- TECHNOLOGY
- TEKNIKVETENSKAP
- Computer science
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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