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Relationship between the Incidence of Type 1 Diabetes and Enterovirus Infections in Different European Populations : Results from the EPIVIR Project
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- Viskari, Hanna (författare)
- JDRF Center for Prevention of Type 1 Diabetes, Finland and Department of Virology, University of Tampere, Tampere, Finland
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- Ludvigsson, Johnny (författare)
- Östergötlands Läns Landsting,Linköpings universitet,Pediatrik,Hälsouniversitetet,Barn- och ungdomskliniken i Linköping
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- Uibo, Raivo (författare)
- Department of Immunology, University of Tartu, Tartu, Estonia
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- Salur, Lina (författare)
- Department of Immunology, University of Tartu, Tartu, Estonia
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- Marciulionyte, Dalia (författare)
- Institute of Endocrinology, Kaunas University of Medicine, Lithuania
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- Hermann, Robert (författare)
- Department of Pediatrics, University of Pécs, Pécs, Hungary
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- Soltesz, Gyula (författare)
- Department of Pediatrics, University of Pécs, Pécs, Hungary
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- Fuchtenbusch, Martin (författare)
- Diabetes Research Institute, Münich, Germany
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- Ziegler, Anette-G (författare)
- Diabetes Research Institute, Münich, Germany
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- Kondrashova, Anita (författare)
- JDRF Center for Prevention of Type 1 Diabetes, Finland, Department of Virology, University of Tampere, Tampere, Finland, Department of Pediatrics, University of Petrozavodsk, Russia
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- Romanov, Anatolij (författare)
- Department of Pediatrics, University of Petrozavodsk, Russia
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- Knip, Mikael (författare)
- JDRF Center for Prevention of Type 1 Diabetes, Finland, Hospital for Children and Adolescents, University of Helsinki, Helsinki, Finland, Department of Pediatrics, Tampere University Hospital, Tampere, Finland
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- Hyoty, Heikki (författare)
- JDRF Center for Prevention of Type 1 Diabetes, Finland, Department of Virology, University of Tampere, Tampere, Finland, Department of Clinical Microbiology, Center for Laboratory Medicine, Tampere University Hospital, Tampere, Finland
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(creator_code:org_t)
- 2004-02-13
- 2004
- Engelska.
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Ingår i: Journal of Medical Virology. - : John Wiley & Sons. - 0146-6615 .- 1096-9071. ; 72:4, s. 610-617
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- The incidence of type 1 diabetes varies markedly between countries. As enterovirus infections have been linked to type 1 diabetes, we determined whether this variation correlates with the frequency of enterovirus infections in different Caucasian populations in Europe. Enterovirus antibodies were examined in the background population (1-year-old and 10-14-year-old children) in seven countries with either exceptionally high (Finland and Sweden) or low/intermediate incidence of diabetes (Estonia, Germany, Hungary, Lithuania, Russia) using EIA and neutralisation assays. Enterovirus antibodies were less frequent in countries with high diabetes incidence compared to countries with low diabetes incidence (P < 0.001). This suggests that enterovirus infections are not particularly common in countries with high diabetes incidence. In contrast, there seems to be an inverse correlation between the incidence of type 1 diabetes and enterovirus infections in the background population, which is in line with the previously proposed polio hypothesis according to which the complications of enterovirus infections become more common in an environment with a decreased rate of infections. © 2004 Wiley-Liss, Inc.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
Nyckelord
- Antibody
- Enterovirus
- Epidemiology
- IgG
- Type 1 diabetes
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Viskari, Hanna
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Ludvigsson, John ...
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Uibo, Raivo
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Salur, Lina
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Marciulionyte, D ...
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Hermann, Robert
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visa fler...
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Soltesz, Gyula
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Fuchtenbusch, Ma ...
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Ziegler, Anette- ...
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Kondrashova, Ani ...
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Romanov, Anatoli ...
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Knip, Mikael
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Hyoty, Heikki
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