Fluid restriction in heart failure patients: Is it useful? The design of a prospective, randomised study

Holst, M.Malmö högskola,Fakulteten för hälsa och samhälle (HS),Malmö Univ. Sch. of Hlth./Soc., Malmo 205 06, Sweden, Department of Cardiology, Malmö University Hospital, Malmo 205 06, Sweden (författare)

Fluid restriction in heart failure patients : Is it useful? The design of a prospective, randomised study

Thirst is a common and troublesome symptom for patients with moderate to severe heart failure. The pharmacological and non-pharmacological treatment as well as the nature of the disease itself causes increased thirst. There is no evidence in the literature about the usefulness of fluid restriction for heart failure patients. Formerly, when very little pharmacological treatment was available, fluid restriction was one of the few interventional options but nowadays when the pharmacological treatment has improved, its importance may be questioned. This article describes the design of an ongoing study with the aim to determine if an individualised and less restrictive fluid prescription can improve the quality of life, cardiac function and exercise capacity, and decrease in hospital admissions and thirst. This study will be performed as a two-group, 1:1 randomised cross-over study. In group 1, the patients are instructed to comply with a maximum fluid intake of 1.5 l. This is a standard treatment today. In group 2, the patients are recommended to intake a fluid, based on the physiological need of 30 ml/kg body weight/24 h, and are allowed to increase the fluid intake to a maximum of 35 ml/kg body weight/24 h. After 16 weeks, the patients will cross over to the other intervention strategy and continue for another 16 weeks. © 2003 European Society of Cardiology. Published by Elsevier B.V. All rights reserved.

Stromberg, A. (författare)
Lindholm, M.Malmö högskola,Fakulteten för hälsa och samhälle (HS),Malmö Univ. Sch. of Hlth./Soc., Malmo 205 06, Sweden (författare)
Uden, G.Malmö högskola,Fakulteten för hälsa och samhälle (HS),Malmö Univ. Sch. of Hlth./Soc., Malmo 205 06, Sweden (författare)
Willenheimer, RonnieLund University,Lunds universitet,Kardiologiska klinikens forskargrupp,Forskargrupper vid Lunds universitet,Cardiology Research Group,Lund University Research Groups,Department of Cardiology, Malmö University Hospital, Malmo 205 06, Sweden(Swepub:lu)medf-rw0 (författare)
Malmö högskolaFakulteten för hälsa och samhälle (HS) (creator_code:org_t)

Ingår i:European Journal of Cardiovascular Nursing: Elsevier Science2:3, s. 237-2421474-51511873-1953

Av författaren/redakt...: Holst, M.; Stromberg, A.; Lindholm, M.; Uden, G.; Willenheimer, Ro ...

Om ämnet

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Kardiologi

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