Sökning: onr:"swepub:oai:DiVA.org:liu-47783" >
Increased concentra...
Increased concentrations of polychlorinated biphenyls, hexachlorobenzene, and chlordanes in mothers of men with testicular cancer
-
Hardell, L (författare)
-
van Bavel, B (författare)
-
Lindstrom, G (författare)
-
visa fler...
-
Carlberg, M (författare)
-
Dreifaldt, AC (författare)
-
Wijkstrom, H (författare)
-
- Starkhammar, Hans (författare)
- Östergötlands Läns Landsting,Linköpings universitet,Hälsouniversitetet,Onkologi,Onkologiska kliniken US
-
- Eriksson, Mikael (författare)
- Lund University,Lunds universitet,Bröstcancer-genetik,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Breastcancer-genetics,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine
-
Hallquist, A (författare)
-
Kolmert, T (författare)
-
visa färre...
-
(creator_code:org_t)
- Environmental Health Perspectives, 2003
- 2003
- Engelska.
-
Ingår i: Journal of Environmental Health Perspectives. - : Environmental Health Perspectives. - 0091-6765 .- 1552-9924. ; 111:7, s. 930-934
- Relaterad länk:
-
https://doi.org/10.1...
-
visa fler...
-
http://www.ehponline... (free)
-
http://dx.doi.org/10...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
https://lup.lub.lu.s...
-
http://kipublication...
-
visa färre...
Abstract
Ämnesord
Stäng
- An increasing incidence of testicular cancer has been reported from several countries in the Western world during the last decades. According to current hypothesis, testicular cancer is initiated during the fetal period, and exposure to endocrine disruptors, i.e., xenoestrogens, has been of concern. In this investigation we studied the concentrations of the sum of 38 polychlorinated biphenyls (PCBs), p,p'-dichlorodiphenyl-dichloroethylene, hexachlorobenzene (HCB), and chlordanes, in 61 cases with testicular cancer and 58 age-matched controls. Furthermore, case and control mothers were also asked to participate, and 44 case mothers and 45 control mothers agreed. They were of similar age. In cases only the concentration on lipid basis of cis-nonachlordane was significantly increased, whereas case mothers showed significantly increased concentrations of the sum of PCBs, HCB, trans- and cis-nonachlordane, and the sum of chlordanes. Among case mothers the sum of PCBs yielded an odds ratio (OR) of 3.8, 95% confidence interval (CI), 1.4-10 was calculated using the median concentration for the control mothers as cutoff value. For HCB, OR = 4.4 (95% CI, 1.7-12), for trans-nonachlordane, OR = 4.1 (95% CI, 1.5-11), for cis-nonachlordane, OR = 3.1 (95% CI, 1.2-7.8), and for sum of chlordanes, OR = 1.9 (95% CI, 0.7-5.0). No consistent different risk pattern was found for seminoma. or nonseminoma testicular cancer.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
Nyckelord
- chlordanes
- fetal period
- hexachlorobenzene
- persistent organic pollutants
- polychlorinated biphenyls
- testicular cancer
- MEDICINE
- MEDICIN
- testicular cancer
- pollutants
- persistent organic
- hexachlorobenzene
- chlordanes
- fetal period
- polychlorinated biphenyls
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Hardell, L
-
van Bavel, B
-
Lindstrom, G
-
Carlberg, M
-
Dreifaldt, AC
-
Wijkstrom, H
-
visa fler...
-
Starkhammar, Han ...
-
Eriksson, Mikael
-
Hallquist, A
-
Kolmert, T
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Hälsovetenskap
-
och Arbetsmedicin oc ...
- Artiklar i publikationen
-
Journal of Envir ...
- Av lärosätet
-
Linköpings universitet
-
Lunds universitet
-
Karolinska Institutet