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- Markl, MichaelUniversity Hospital Freiburg (författare)
Comprehensive 4D velocity mapping of the heart and great vessels by cardiovascular magnetic resonance
- Artikel/kapitelEngelska2011
Förlag, utgivningsår, omfång ...
- Taylor andamp; Francis / BioMed Central,2011
- electronicrdacarrier
Nummerbeteckningar
- LIBRIS-ID:oai:DiVA.org:liu-65944
- https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-65944URI
- https://doi.org/10.1186/1532-429X-13-7DOI
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- Språk:engelska
- Sammanfattning på:engelska
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- This is an electronic version of an article published in: Michael Markl, Philip J Kilner and Tino Ebbers, Comprehensive 4D velocity mapping of the heart and great vessels by cardiovascular magnetic resonance, 2011, JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE, (13), 7. http://dx.doi.org/10.1186/1532-429X-13-7 Licensee: BioMed Central
- Background: Phase contrast cardiovascular magnetic resonance (CMR) is able to measure all three directional components of the velocities of blood flow relative to the three spatial dimensions and the time course of the heart cycle. In this article, methods used for the acquisition, visualization, and quantification of such datasets are reviewed and illustrated. Methods: Currently, the acquisition of 3D cine (4D) phase contrast velocity data, synchronized relative to both cardiac and respiratory movements takes about ten minutes or more, even when using parallel imaging and optimized pulse sequence design. The large resulting datasets need appropriate post processing for the visualization of multidirectional flow, for example as vector fields, pathlines or streamlines, or for retrospective volumetric quantification. Applications: Multidirectional velocity acquisitions have provided 3D visualization of large scale flow features of the healthy heart and great vessels, and have shown altered patterns of flow in abnormal chambers and vessels. Clinically relevant examples include retrograde streams in atheromatous descending aortas as potential thromboembolic pathways in patients with cryptogenic stroke and marked variations of flow visualized in common aortic pathologies. Compared to standard clinical tools, 4D velocity mapping offers the potential for retrospective quantification of flow and other hemodynamic parameters. Conclusions: Multidirectional, 3D cine velocity acquisitions are contributing to the understanding of normal and pathologically altered blood flow features. Although more rapid and user-friendly strategies for acquisition and analysis may be needed before 4D velocity acquisitions come to be adopted in routine clinical CMR, their capacity to measure multidirectional flows throughout a study volume has contributed novel insights into cardiovascular fluid dynamics in health and disease.
Ämnesord och genrebeteckningar
- MEDICINE
- MEDICIN
Biuppslag (personer, institutioner, konferenser, titlar ...)
- Kilner, Philip JRoyal Brompton (författare)
- Ebbers, TinoLinköpings universitet,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Fysiologi,Hälsouniversitetet,Mekanisk värmeteori och strömningslära(Swepub:liu)tineb49 (författare)
- University Hospital FreiburgRoyal Brompton (creator_code:org_t)
Sammanhörande titlar
- Ingår i:JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE: Taylor andamp; Francis / BioMed Central13:71097-6647
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- JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE (Sök värdpublikationen i LIBRIS)
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- Markl, Michael
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