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Thoracic epidural a...
Thoracic epidural analgesia or patient-controlled local analgesia for radical retropubic prostatectomy: a randomized, double-blind study
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- Fant, Federica (författare)
- Örebro universitet,Institutionen för hälsovetenskap och medicin,Örebro University
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- Axelsson, Kjell (författare)
- Örebro universitet,Institutionen för hälsovetenskap och medicin,Örebro University
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- Sandblom, Dag (författare)
- Örebro universitet,Institutionen för hälsovetenskap och medicin,Örebro University
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- Magnuson, A (författare)
- Clinical Epidemiology and Biostatistical Unit, Örebro University Hospital, Örebro University, Örebro, Sweden
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- Andersson, Swen-Olof (författare)
- Örebro universitet,Institutionen för hälsovetenskap och medicin,Örebro University
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- Gupta, Anil (författare)
- Örebro universitet,Östergötlands Läns Landsting,Linköpings universitet,Anestesiologi med intensivvård,Hälsouniversitetet,Anestesi- och operationkliniken US,Institutionen för hälsovetenskap och medicin
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(creator_code:org_t)
- Oxford University Press (OUP), 2011
- 2011
- Engelska.
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Ingår i: British Journal of Anaesthesia. - : Oxford University Press (OUP). - 0007-0912 .- 1471-6771. ; 107:5, s. 782-789
- Relaterad länk:
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http://bjanaesthesia...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Background. Postoperative pain after radical retropubic prostatectomy is moderate to severe. The primary aim of this study was to assess whether intra-abdominal local anaesthetics provide similar analgesia compared with thoracic epidural analgesia (TEA). less thanbrgreater than less thanbrgreater thanMethods. Fifty patients, ASA I-II, participated in this prospective, double-blinded study. All patients had TEA. After operation, they were randomized into two groups of 25 patients: Group PCLA (patient-controlled local analgesia): self-administration of 10 ml of ropivacaine 2 mg ml(-1) via the intra-abdominal catheter for 48 h. Group TEA: infusion of 10 ml h(-1) of ropivacaine 1 mg ml(-1), fentanyl 2 mg ml(-1), and epinephrine 2 mg ml 21 epidurally for 48 h. The primary endpoint was pain on coughing at 4 h after operation. Rescue medication was morphine i.v. as required. less thanbrgreater than less thanbrgreater thanResults. Pain on coughing at 4, 24, and 48 h was significantly lower in Group TEA [0 (0-10)] compared with Group PCLA [4 (0-10)] (Pandlt;0.05). Significantly lower pain intensity was also found in Group TEA compared with Group PCLA at the incision site, deep pain, and pain on coughing at 4 and 24 h (Pandlt;0.05). Morphine consumption was significantly greater in Group PCLA [12 (0-46)] compared with Group TEA [0 (0-20)] at 0-48 h after operation [median (range)] (P=0.015). Maximum expiratory pressure was higher in Group TEA compared with Group PCLA at 24 h (Pandlt;0.01). less thanbrgreater than less thanbrgreater thanConclusions. TEA provides superior postoperative pain relief with better preservation of expiratory muscle strength compared with PCLA.
Nyckelord
- anaesthetics
- local
- analgesia
- epidural
- analgesia
- patient-controlled
- prostatectomy
- retropubic
- MEDICINE
- MEDICIN
- Medicine
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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