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Breast cancer risk ...
Breast cancer risk after radiotherapy in infancy : a pooled analysis of two Swedish cohorts of 17,202 infants
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- Lundell, Marie (författare)
- Karolinska Institutet
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- Mattsson, Anders (författare)
- Radiumhemmet, Karolinska Hospital, Stockholm
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- Karlsson, Per (författare)
- Sahlgrenska University Hospital, Gothenburg
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- Holmberg, Erik (författare)
- Sahlgrenska University Hospital, Gothenburg
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- Gustafsson, Agnetha, 1960- (författare)
- Sahlgrenska University Hospital, Gothenburg
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- Holm, Lars-Erik (författare)
- Swedish Radiation Protection Institute, Solna
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(creator_code:org_t)
- Radiation Research Society, 1999
- 1999
- Engelska.
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Ingår i: Radiation Research. - : Radiation Research Society. - 0033-7587 .- 1938-5404. ; 151:5, s. 626-632
- Relaterad länk:
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http://www.jstor.org...
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https://urn.kb.se/re...
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http://kipublication...
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https://doi.org/10.2...
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Abstract
Ämnesord
Stäng
- The incidence of breast cancer was studied in a cohort of 17,202 women irradiated for skin hemangioma in infancy at the Radiumhemmet, Stockholm, or the Sahlgrenska University Hospital, Gothenburg. A major part of the cohort had been treated with radium-226 applicators, and the mean absorbed dose to the breasts was 0.29 Gy (range <0.01-35.8 Gy). Two hundred forty-five breast cancers were diagnosed in the cohort during the period 1958-1993, and the standardized incidence ratio (SIR) was 1.20 (95% CI 1.06-1.36). Different dose-response models were tested, and a linear model gave the best fit. Neither age at exposure, breast dose rate, ovarian dose nor time since exposure had any statistically significant modifying effect, and breast dose was the only determinant of risk. The excess relative risk per gray (ERR/Gy) was 0.35 (95% CI 0.18-0.59), which is lower than in most other studies.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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