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Preoperative Topica...
Preoperative Topical Hypothermia used in Prolonged Severe Lower Limb Ischemia to Avoid Ischemic Damage - The First Clinical Experience
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- Forsell, Claes (författare)
- Linköpings universitet,Avdelningen för kardiovaskulär medicin,Hälsouniversitetet
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- Åberg, Jonas (författare)
- Linköpings universitet,Avdelningen för kardiovaskulär medicin,Hälsouniversitetet
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- Szabó, Zoltán (författare)
- Östergötlands Läns Landsting,Linköpings universitet,Avdelningen för kardiovaskulär medicin,Hälsouniversitetet,Thorax-kärlkliniken i Östergötland
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(creator_code:org_t)
- 2013
- 2013
- Engelska.
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Ingår i: International Journal of Biomedical Science. - 1550-9702 .- 1555-2810. ; 9:3, s. 181-184
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Abstract
Ämnesord
Stäng
- Severe lower limb ischemia TASC IIB/III with sensory and motor neurologic deficiencies leads to prolonged hospital care, amputation, and death in 20-70 % of cases. We present our first clinical experience of the use of preoperative topical hypothermia to improve muscular viability in these patients. Two hours after onset of symptoms, six 4-liter plastic bags were filled with snow and packed against the ischemic leg which was protected from frost injury by a layer of towels. After surgical revascularization four hours later muscular and neural functions in the leg were completely restored. A maximum serum myoglobin of 6500 ng/L (median 12000 ng/L in similar but untreated patients) postoperatively decreased to 1400 ng/L after 27 hours.
Nyckelord
- skeletal muscle; topical hypothermia; limb ischemia; ischemic damage; protection
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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