Sökning: onr:"swepub:oai:DiVA.org:liu-98855" >
Mouse JunD negative...
Mouse JunD negatively regulates fibroblast growth and antagonizes transformation by ras
-
- Pfarr, C. M. (författare)
- Département des Biotechnologies, Institut Pasteur, Paris, France
-
- Mechta, F. (författare)
- Département des Biotechnologies, Institut Pasteur, Paris, France
-
- Spyrou, Giannis (författare)
- Département des Biotechnologies, Institut Pasteur, Paris, France
-
visa fler...
-
- Lallemand, D. (författare)
- Département des Biotechnologies, Institut Pasteur, Paris, France
-
- Carillo, S. (författare)
- Institut de Genetique Moleculaire de Montpellier Unité Mixte de Recherche, Montpellier, France
-
- Yaniv, M. (författare)
- Département des Biotechnologies, Institut Pasteur, Paris, France
-
visa färre...
-
(creator_code:org_t)
- Cell Press, 1994
- 1994
- Engelska.
-
Ingår i: Cell. - : Cell Press. - 0092-8674 .- 1097-4172. ; 76:4, s. 747-760
- Relaterad länk:
-
http://www.sciencedi...
-
visa fler...
-
https://urn.kb.se/re...
-
visa färre...
Abstract
Ämnesord
Stäng
- As NIH 3T3 fibroblasts become quiescent, the level of c-Jun protein decreases while JunD accumulates. When resting cells are stimulated with fresh serum, nuclear-localized JunD is rapidly degraded, followed by resynthesis of both c-Jun and JunD later in G1. Overexpression of JunD results in slower growth and an increase in the percentage of cells in G0/G1 while c-Jun overexpression produces larger S/G2 and M phase populations. In addition, JunD partially suppresses transformation by an activated ras gene whereas c-Jun cooperates with ras to transform cells. These data indicate that two closely related transcription factors can function in an opposing manner.
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
-
Cell
(Sök värdpublikationen i LIBRIS)
Till lärosätets databas