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Trends, geographica...
Trends, geographical variation and factors associated with the use of anti-VEGF intravitreal injections in Portugal (2013–2018): a retrospective analysis of administrative data
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- Rocha, João Victor (författare)
- NOVA University Lisbon, Portugal
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- Marques, Ana Patricia (författare)
- NOVA University Lisbon, Portugal
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- Macedo, António Filipe, Senior Lecturer, 1976- (författare)
- Linnéuniversitetet,Institutionen för medicin och optometri (MEO),Hållbar hälsa
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- Afonso-Silva, Marta (författare)
- Novartis Farma Produtos Farmacêuticos SA, Portugal
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- Laires, Pedro (författare)
- NOVA University Lisbon, Portugal;Novartis Farma Produtos Farmacêuticos SA, Portugal
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- Almeida, Ana Sofia (författare)
- Novartis Farma Produtos Farmacêuticos SA, Portugal
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- Fernandes, Julieta (författare)
- Novartis Farma Produtos Farmacêuticos SA, Portugal
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- Pardal, Marisa (författare)
- Novartis Farma Produtos Farmacêuticos SA, Portugal
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- Santana, Rui (författare)
- NOVA University Lisbon, Portugal
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(creator_code:org_t)
- 2022-04-06
- 2022
- Engelska.
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Ingår i: BMJ Open. - : BMJ Publishing Group Ltd. - 2044-6055. ; 12:4
- Relaterad länk:
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https://doi.org/10.1...
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http://bmjopen.bmj.c...
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https://lnu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
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- Aims The arrival of anti-vascular endothelial growth factor (anti-VEGF) therapies represented a treatment shift for several ophthalmological disorders and led to an increasing number of patients undergoing intravitreal injections. The aims of this observational study were to assess the expansion of anti-VEGF intravitreal injections in the Portuguese National Health System (NHS) and to identify factors correlated with geographical variations in episode rates.Methods Administrative database on discharge from Portuguese NHS hospitals was analysed for annual values and rates of intravitreal anti-VEGF injections at a national and regional level, between 2013 and 2018.Results The number of episodes of anti-VEGF treatment and patients treated increased 16% and 9% per year, respectively, between 2013 and 2018. During the study period around 72% of patients were treated in the Metropolitan areas of Lisbon and Porto and in the Central region. Intravitreal anti-VEGF treatment rates in 2018 were 560 per 100 000 population and presented high variability between municipalities. Higher anti-VEGF treatment rates at the municipality level were associated with shorter distances between their residence and the hospital. At the hospital level, higher ratio of ophthalmologists and higher organisational level were associated with higher anti-VEGF treatment rates.Conclusion The number of episodes and patients treated with anti-VEGF injections has been growing in recent years. Proximity to healthcare, more access to ophthalmologists and hospitals with higher organisational levels are associated with higher anti-VEGF treatment rates. Improving access is crucial to reduce regional discrepancies and ensure optimal treatment frequency, which may improve health outcomes.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Oftalmologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Ophthalmology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Annan medicin och hälsovetenskap -- Övrig annan medicin och hälsovetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Other Medical and Health Sciences -- Other Medical and Health Sciences not elsewhere specified (hsv//eng)
Nyckelord
- Proliferative diabetic retinopathy
- Retinal oedema
- Choroidal neovascularisation
- Retinal vein occlusion
- anti-VEGF intravitreal injections
- Neovascular age-related macular degeneration
- Diabetic macular oedema
- Optometry
- Optometri
- Medicin
- Medicine
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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