Sökning: onr:"swepub:oai:DiVA.org:lnu-111650" > Internet-Based Cogn...
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000 | 14233naa a2201513 4500 | |
001 | oai:DiVA.org:lnu-111650 | |
003 | SwePub | |
008 | 220429s2021 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:liu-203190 | |
009 | oai:prod.swepub.kib.ki.se:145623858 | |
009 | oai:gup.ub.gu.se/304532 | |
009 | oai:DiVA.org:su-193532 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-1116502 URI |
024 | 7 | a https://doi.org/10.1001/jamapsychiatry.2020.43642 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-2031902 URI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1456238582 URI |
024 | 7 | a https://gup.ub.gu.se/publication/3045322 URI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-1935322 URI |
040 | a (SwePub)lnud (SwePub)liud (SwePub)kid (SwePub)gud (SwePub)su | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a for2 swepub-publicationtype |
100 | 1 | a Karyotaki, Eiriniu University of Bern, Switzerland;Vrije Universiteit Amsterdam, Netherlands;Harvard Medical School, USA,Univ Bern, Inst Social & Prevent Med, Bern, Switzerland.;Vrije Univ Amsterdam, Dept Clin Neuro & Dev Psychol, Amsterdam, Netherlands.;Harvard Med Sch, Dept Global Hlth & Social Med, 641 Huntington Ave, Boston, MA 02115 USA4 aut |
245 | 1 0 | a Internet-Based Cognitive Behavioral Therapy for Depression :b A Systematic Review and Individual Patient Data Network Meta-analysis |
264 | 1 | b American Medical Association,c 2021 |
338 | a print2 rdacarrier | |
500 | a Carlbring and Johansson are part of the Individual Patient Data Meta-Analyses for Depression (IPDMA-DE) Collaboration, which is included as co-author of the article. | |
520 | a IMPORTANCE: Personalized treatment choices would increase the effectiveness of internet-based cognitive behavioral therapy (iCBT) for depression to the extent that patients differ in interventions that better suit them.OBJECTIVE: To provide personalized estimates of short-term and long-term relative efficacy of guided and unguided iCBT for depression using patient-level information.DATA SOURCES: We searched PubMed, Embase, PsycInfo, and Cochrane Library to identify randomized clinical trials (RCTs) published up to January 1, 2019.STUDY SELECTION: Eligible RCTs were those comparing guided or unguided iCBT against each other or against any control intervention in individuals with depression. Available individual patient data (IPD) was collected from all eligible studies. Depression symptom severity was assessed after treatment, 6 months, and 12 months after randomization.DATA EXTRACTION AND SYNTHESIS: We conducted a systematic review and IPD network meta-analysis and estimated relative treatment effect sizes across different patient characteristics through IPD network meta-regression.MAIN OUTCOMES AND MEASURES: Patient Health Questionnaire-9 (PHQ-9) scores.RESULTS: Of 42 eligible RCTs, 39 studies comprising 9751 participants with depression contributed IPD to the IPD network meta-analysis, of which 8107 IPD were synthesized. Overall, both guided and unguided iCBT were associated with more effectiveness as measured by PHQ-9 scores than control treatments over the short term and the long term. Guided iCBT was associated with more effectiveness than unguided iCBT (mean difference [MD] in posttreatment PHQ-9 scores, -0.8; 95% CI, -1.4 to -0.2), but we found no evidence of a difference at 6 or 12 months following randomization. Baseline depression was found to be the most important modifier of the relative association for efficacy of guided vs unguided iCBT. Differences between unguided and guided iCBT in people with baseline symptoms of subthreshold depression (PHQ-9 scores 5-9) were small, while guided iCBT was associated with overall better outcomes in patients with baseline PHQ-9 greater than 9.CONCLUSIONS AND RELEVANCE: In this network meta-analysis with IPD, guided iCBT was associated with more effectiveness than unguided iCBT for individuals with depression, benefits were more substantial in individuals with moderate to severe depression. Unguided iCBT was associated with similar effectiveness among individuals with symptoms of mild/subthreshold depression. Personalized treatment selection is entirely possible and necessary to ensure the best allocation of treatment resources for depression. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Psykiatri0 (SwePub)302152 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Psychiatry0 (SwePub)302152 hsv//eng |
650 | 7 | a SAMHÄLLSVETENSKAPx Psykologix Psykologi0 (SwePub)501012 hsv//swe |
650 | 7 | a SOCIAL SCIENCESx Psychologyx Psychology0 (SwePub)501012 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Allmänmedicin0 (SwePub)302242 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex General Practice0 (SwePub)302242 hsv//eng |
650 | 7 | a SAMHÄLLSVETENSKAPx Psykologix Tillämpad psykologi0 (SwePub)501022 hsv//swe |
650 | 7 | a SOCIAL SCIENCESx Psychologyx Applied Psychology0 (SwePub)501022 hsv//eng |
650 | 7 | a SAMHÄLLSVETENSKAPx Psykologi0 (SwePub)5012 hsv//swe |
650 | 7 | a SOCIAL SCIENCESx Psychology0 (SwePub)5012 hsv//eng |
653 | a Cognitive Behavioral Therapy | |
653 | a Depression Therapy | |
653 | a Depressive Disorder Therapy | |
653 | a Humans | |
653 | a Internet-Based Intervention | |
653 | a Network Meta-Analysis | |
653 | a Psychology | |
653 | a Psykologi | |
653 | a Psychology | |
700 | 1 | a Efthimiou, Orestisu University of Bern, Switzerland;University of Oxford, UK,Univ Bern, Inst Social & Prevent Med, Bern, Switzerland.;Univ Oxford, Dept Psychiat, Oxford, England4 aut |
700 | 1 | a Miguel, Clarau Vrije Universiteit Amsterdam, Netherlands;Amsterdam Public Health Research Institute, Netherlands,Vrije Univ Amsterdam, Dept Clin Neuro & Dev Psychol, Amsterdam, Netherlands.;Amsterdam Publ Hlth Res Inst, Amsterdam, Netherlands4 aut |
700 | 1 | a Bermpohl, Frederic Maas Genanntu University of Wuppertal, Germany,Univ Wuppertal, Dept Clin Psychol & Psychotherapy, Wuppertal, Germany. Kyoto Univ, Dept Hlth Promot & Human Behav, Dept Clin Epidemiol, Grad Sch Med,Sch Publ Hlth, Kyoto, Japan4 aut |
700 | 1 | a Furukawa, Toshi Au University of Wuppertal, Germany;Kyoto University Graduate School of Medicine/School of Public Health, Japan,Univ Wuppertal, Dept Clin Psychol & Psychotherapy, Wuppertal, Germany. Kyoto Univ, Dept Hlth Promot & Human Behav, Dept Clin Epidemiol, Grad Sch Med,Sch Publ Hlth, Kyoto, Japan4 aut |
700 | 1 | a Cuijpers, Pimu Vrije Universiteit Amsterdam, Netherlands;Amsterdam Public Health Research Institute, Netherlands,Vrije Univ Amsterdam, Dept Clin Neuro & Dev Psychol, Amsterdam, Netherlands.;Amsterdam Publ Hlth Res Inst, Amsterdam, Netherlands4 aut |
700 | 1 | a Riper, Heleenu Vrije Universiteit Amsterdam, Netherlands;Amsterdam Public Health Research Institute, Netherlands;GGZ inGeest, Netherlands4 aut |
700 | 1 | a Patel, Vikramu Harvard Medical School, Sweden4 aut |
700 | 1 | a Mira, Adrianau MINECO, Spain;Valencia University, Spain4 aut |
700 | 1 | a Gemmil, Alan W.u Heidelberg Repatriation Hospital, Australia4 aut |
700 | 1 | a Yeung, Albert S.u Harvard University, USA4 aut |
700 | 1 | a Lange, Alfredu University of Amsterdam, Netherlands4 aut |
700 | 1 | a Williams, Alishia D.u University of New South Wales, Australia4 aut |
700 | 1 | a Mackinnon, Andrewu University of New South Wales, Australia; University of Melbourne, Australia4 aut |
700 | 1 | a Geraedts, Annau HumanTotalCare, Netherlands4 aut |
700 | 1 | a van Straten, Annemiekeu Vrije Universiteit Amsterdam, Netherlands;Amsterdam Public Health Research Institute, Netherlands4 aut |
700 | 1 | a Meyer, Björnu Gaia AG, Germany;University of London, UK4 aut |
700 | 1 | a Björkelund, Cecilia,d 1948u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine4 aut0 (Swepub:gu)xbjoce |
700 | 1 | a Knaevelsrud, Christineu Freie Universität Berlin, Germany4 aut |
700 | 1 | a Beevers, Christopher G.u The University of Texas at Austin, USA4 aut |
700 | 1 | a Botella, Cristinau Jaume I University, Spain;Instituto Salud Carlos III, Spain4 aut |
700 | 1 | a Strunk, Daniel R.u The Ohio State University, USA4 aut |
700 | 1 | a Mohr, David C.u Northwestern University, USA4 aut |
700 | 1 | a Ebert, David D.u Friedrich-Alexander-University Erlangen-Nürnberg, Germany4 aut |
700 | 1 | a Kessler, Davidu University of Bristol, UK;National Institute for Health Research Bristol Biomedical Research Centre, UK4 aut |
700 | 1 | a Richards, Dereku Trinity College Dublin School of Psychology, Ireland;SilverCloud Health, Ireland4 aut |
700 | 1 | a Littlewood, Elizabethu University of York, UK4 aut |
700 | 1 | a Forsell, Eriku Karolinska Institutet, Sweden;Region Stockholm, Sweden4 aut |
700 | 1 | a Feng, Fanu Massachusetts General Hospital, USA4 aut |
700 | 1 | a Wang, Fangu China Academy of Chinese Medical Sciences, China4 aut |
700 | 1 | a Andersson, Gerhard,c Professor,d 1988-u Linköpings universitet,Psykologi,Filosofiska fakulteten,Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet & Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden4 aut0 (Swepub:liu)geran87 |
700 | 1 | a Hadjistavropoulos, Heatheru University of Regina, Canada4 aut |
700 | 1 | a Christensen, Heleenu University of New South Wales, Australia4 aut |
700 | 1 | a Ezawa, Iony D.u The Ohio State University, USA4 aut |
700 | 1 | a Choi, Isabellau University of Sydney, Australia4 aut |
700 | 1 | a Rosso, Isabelle Mu McLean Hospital, USA;Harvard Medical School, USA4 aut |
700 | 1 | a Klein, Jan Philippu Lübeck University, Germany4 aut |
700 | 1 | a Shumake, Jasonu The University of Texas at Austin, USA4 aut |
700 | 1 | a Garcia-Campayo, Javieru Miguel Servet University Hospital, Spain;RedIAPP, Spain4 aut |
700 | 1 | a Milgrom, Jeannetteu Heidelberg Repatriation Hospital, Australia4 aut |
700 | 1 | a Smith, Jessicau Imperial College London, UK4 aut |
700 | 1 | a Montero-Marin, Jesusu University of Oxford, UK4 aut |
700 | 1 | a Newby, Jill M.u University of New South Wales, Australia4 aut |
700 | 1 | a Bretón-López, Juanau Jaume I University, Spain;Instituto Salud Carlos III, Spain4 aut |
700 | 1 | a Schneider, Justineu University of Nottingham, UK4 aut |
700 | 1 | a Vernmark, Kristofer,d 1976-u Linköpings universitet,Psykologi,Filosofiska fakulteten,Psykologpartners, Linköping, Sweden4 aut0 (Swepub:liu)krive80 |
700 | 1 | a Bücker, Larau University Medical Center Hamburg-Eppendorf, Germany4 aut |
700 | 1 | a Sheeber, Lisa B.u Oregon Research Institute, USA4 aut |
700 | 1 | a Warmerdam, Lisanneu National Health Care Institute, Netherlands4 aut |
700 | 1 | a Farrer, Louiseu The Australian National University, Australia4 aut |
700 | 1 | a Heinrich, Manuelu Freie Universität Berlin, Germany4 aut |
700 | 1 | a Huibers, Marcus J. H.u Vrije Universiteit Amsterdam, Netherlands;Amsterdam Public Health Research Institute, Netherlands4 aut |
700 | 1 | a Kivi, Marieu Gothenburg University,Göteborgs universitet,Psykologiska institutionen,Department of Psychology4 aut0 (Swepub:gu)xkivma |
700 | 1 | a Kraepelien, Martinu Karolinska Institutet, Sweden;Region Stockholm, Sweden4 aut |
700 | 1 | a Forand, Nicholas R.u The Ohio State University Wexner Medical Center, USA;The Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, USA4 aut |
700 | 1 | a Pugh, Nickyu University of Regina, Canada4 aut |
700 | 1 | a Lindefors, Nilsu Karolinska Institutet, Sweden;Region Stockholm, Sweden4 aut |
700 | 1 | a Lintvedt, Oveu Norwegian Center for E-health research, Norway4 aut |
700 | 1 | a Zagorscak, Pavleu Freie Universität Berlin, Germany4 aut |
700 | 1 | a Carlbring, Peru Stockholms universitet,Klinisk psykologi4 aut0 (Swepub:su)pecar |
700 | 1 | a Phillips, Rachelu Imperial College London School of Public Health, UK4 aut |
700 | 1 | a Johansson, Robertu Stockholms universitet,Klinisk psykologi4 aut0 (Swepub:su)rojo4696 |
700 | 1 | a Kessler, Ronald C.u Harvard Medical School, USA4 aut |
700 | 1 | a Brabyn, Sallyu SilverCloud Health, Ireland4 aut |
700 | 1 | a Perini, Sarahu The Clinical Psychology Centre, Australia4 aut |
700 | 1 | a Rauch, Scott L.u McLean Hospital, USA4 aut |
700 | 1 | a Gilbody, Simonu University of York, UK;Hull York Medical School, UK4 aut |
700 | 1 | a Moritz, Steffenu University Medical Center Hamburg-Eppendorf, Germany4 aut |
700 | 1 | a Berger, Thomasu University of Bern, Switzerland4 aut |
700 | 1 | a Pop, Victoru Tilburg University, Netherlands4 aut |
700 | 1 | a Kaldo, Viktor,c Professoru Linnéuniversitetet,Institutionen för psykologi (PSY),Karolinska Institutet, Sweden4 aut0 (Swepub:lnu)vikaaa |
700 | 1 | a Spek, Violau Tilburg University, Netherlands4 aut |
700 | 1 | a Forsell, Yvonneu Karolinska Institutet, Sweden;Region Stockholm, Sweden4 aut |
710 | 2 | a University of Bern, Switzerland;Vrije Universiteit Amsterdam, Netherlands;Harvard Medical School, USAb Univ Bern, Inst Social & Prevent Med, Bern, Switzerland.;Vrije Univ Amsterdam, Dept Clin Neuro & Dev Psychol, Amsterdam, Netherlands.;Harvard Med Sch, Dept Global Hlth & Social Med, 641 Huntington Ave, Boston, MA 02115 USA4 org |
773 | 0 | t JAMA psychiatryd : American Medical Associationg 78:4, s. 361-371q 78:4<361-371x 2168-6238x 2168-622X |
856 | 4 | u https://boris.unibe.ch/151988/1/Karyotaki_JAMAPsychiatry_2021_epub.pdf |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-111650 |
856 | 4 8 | u https://doi.org/10.1001/jamapsychiatry.2020.4364 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-203190 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:145623858 |
856 | 4 8 | u https://gup.ub.gu.se/publication/304532 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-193532 |
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