Sökning: onr:"swepub:oai:DiVA.org:lnu-89872" >
Differential Effect...
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Ledreux, AurelieUniv Denver, USA
(författare)
Differential Effects of Physical Exercise, Cognitive Training, and Mindfulness Practice on Serum BDNF Levels in Healthy Older Adults : A Randomized Controlled Intervention Study
- Artikel/kapitelEngelska2019
Förlag, utgivningsår, omfång ...
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IOS Press,2019
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:lnu-89872
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https://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-89872URI
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https://doi.org/10.3233/JAD-190756DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:142058017URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
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Previous studies have indicated that an active lifestyle is associated with better brain health and a longer life, compared to a more sedentary lifestyle. These studies, both on human and animal subjects, have typically focused on a single activity, usually physical exercise, but other activities have received an increasing interest. One proposed mechanism is that physical exercise increases levels of brain-derived neurotrophic factor (BDNF) in the brain. For the first time, the long-term effects on serum BDNF levels were compared in persons who engaged in either physical exercise training, cognitive training, or mindfulness practice during 5 weeks, and compared with an active control group. Two cohorts of healthy older individuals, one from the Boston area in the US and one from the Vaxjo area in Sweden, participated. A total of 146 participants were randomly assigned to one of the four groups. All interventions were structurally similar, using interactive, computer-based software that directed participants to carry out specified activities for 35 minutes/day, 5 days per week for 5 weeks. Blood samples were obtained at baseline and soon after the completion of the 5-week long intervention program, and serum BDNF levels were measured using a commercially available ELISA. Only the group that underwent cognitive training increased their serum BDNF levels after 5 weeks of training (F-1,F-74 = 4.22, p = 0.044, partial eta(2) = 0.054), corresponding to an average 10% increase. These results strongly suggest that cognitive training can exert beneficial effects on brain health in an older adult population.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Håkansson, KristerKarolinska Institutet
(författare)
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Carlsson, RogerLinnéuniversitetet,Institutionen för psykologi (PSY)(Swepub:lnu)rocaaa
(författare)
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Tewele, Mhretab KidaneLinnéuniversitetet,Institutionen för psykologi (PSY)(Swepub:lnu)mhteaa
(författare)
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Columbo, LauraMed Univ South Carolina, USA
(författare)
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Terjestam, Yvonne,1953-Linnéuniversitetet,Institutionen för psykologi (PSY)(Swepub:lnu)eteyv
(författare)
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Ryan, ElizaHarvard Med Sch, USA
(författare)
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Tusch, ErichHarvard Med Sch, USA
(författare)
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Winblad, BengtKarolinska Institutet
(författare)
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Daffner, KirkHarvard Med Sch, USA
(författare)
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Granholm, Ann-CharlotteUniv Denver, USA;Med Univ South Carolina, USA;Karolinska Institutet, Sweden
(författare)
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Mohammed, Abdul K. H.Linnéuniversitetet,Institutionen för psykologi (PSY),Karolinska Institutet, Sweden(Swepub:lnu)amosvi
(författare)
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Karolinska InstitutetUniv Denver, USA
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Journal of Alzheimer's Disease: IOS Press71:4, s. 1245-12611387-28771875-8908
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Ledreux, Aurelie
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Håkansson, Krist ...
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Carlsson, Roger
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Tewele, Mhretab ...
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Columbo, Laura
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Terjestam, Yvonn ...
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visa fler...
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Ryan, Eliza
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Tusch, Erich
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Winblad, Bengt
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Daffner, Kirk
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Granholm, Ann-Ch ...
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Mohammed, Abdul ...
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Linnéuniversitetet
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