Sökning: onr:"swepub:oai:DiVA.org:mau-15656" > Effects of clinical...
Fältnamn | Indikatorer | Metadata |
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000 | 04081naa a2200469 4500 | |
001 | oai:DiVA.org:mau-15656 | |
003 | SwePub | |
008 | 200330s2010 | |||||||||||000 ||eng| | |
009 | oai:lup.lub.lu.se:8e110207-eeac-44f1-8239-6a6ca7d70a15 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-156562 URI |
024 | 7 | a https://doi.org/10.1111/j.1574-695X.2010.00707.x2 DOI |
024 | 7 | a https://lup.lub.lu.se/record/16256962 URI |
040 | a (SwePub)maud (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Pihl, Mariau Malmö högskola,Odontologiska fakulteten (OD)4 aut0 (Swepub:mau)odmapih |
245 | 1 0 | a Effects of clinical isolates of Pseudomonas aeruginosa on Staphylococcus epidermidis biofilm formation |
264 | 1 | b Wiley-Blackwell,c 2010 |
338 | a print2 rdacarrier | |
520 | a Pseudomonas aeruginosa is often found in chronic infections, including cystic fibrosis lung infections and those related to chronic wounds and venous ulcers. At the latter sites, P. aeruginosa can be isolated together with Staphylococcus epidermidis, and we have therefore explored the effect of clinical isolates and laboratory strains of P. aeruginosa strains on colonisation by S. epidermidis in dual-species biofilms. Biofilm formation was assayed using 16S rRNA fluorescence in situ hybridization and confocal laser scanning microscopy. Amongst the six P. aeruginosa strains tested, one particular strain, denoted 14:2, exerted a significant inhibitory effect and even after six hours, S. epidermidis levels in dual-species biofilms were reduced by more than 85% compared to biofilms without P. aeruginosa. Interestingly strain 14:2 was found to be negative for classical virulence determinants including pyocyanin, elastase and alkaline protease. Therefore, we suggest that less virulent phenotypes of P. aeruginosa which may develop over time in chronic infections, could counteract colonisation by S. epidermidis, ensuring persistence and dominance by P. aeruginosa in the host micro-habitat. Further studies are required to explain the inhibitory effect on S. epidermidis, although, extracellular polysaccharides produced by P. aeruginosa might play a role in this phenomenon. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Mikrobiologi inom det medicinska området0 (SwePub)301092 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Microbiology in the medical area0 (SwePub)301092 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Dermatologi och venereologi0 (SwePub)302042 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Dermatology and Venereal Diseases0 (SwePub)302042 hsv//eng |
653 | a dual-species biofilms | |
653 | a Adhesion | |
653 | a extracellular products | |
653 | a strain differences | |
653 | a competition | |
700 | 1 | a Chávez de Paz, Luis Eduardo4 aut |
700 | 1 | a Schmidtchen, Arturu Lund University,Lunds universitet,Dermatologi och venereologi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Dermatology and Venereology (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)derm-asc |
700 | 1 | a Svensäter, Gunnelu Malmö högskola,Odontologiska fakulteten (OD)4 aut0 (Swepub:mau)odgusv |
700 | 1 | a Davies, Juliau Malmö högskola,Odontologiska fakulteten (OD)4 aut0 (Swepub:mau)odjuda |
710 | 2 | a Malmö högskolab Odontologiska fakulteten (OD)4 org |
773 | 0 | t FEMS Immunology and Medical Microbiologyd : Wiley-Blackwellg 59:3, s. 504-512q 59:3<504-512x 0928-8244x 1574-695X |
856 | 4 | u http://www.ncbi.nlm.nih.gov/pubmed/20579097?dopt=Abstracty FULLTEXT |
856 | 4 | u http://dx.doi.org/10.1111/j.1574-695X.2010.00707.xy FULLTEXT |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-15656 |
856 | 4 8 | u https://doi.org/10.1111/j.1574-695X.2010.00707.x |
856 | 4 8 | u https://lup.lub.lu.se/record/1625696 |
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