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Is there thrombin-a...
Is there thrombin-activatable fibrinolysis inhibitor in saliva?
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- Chopra, S (författare)
- Karolinska Institutet
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- Friman, E (författare)
- Department of Oral and Maxillofacial Surgery, Karolinska University Hospital, Stockholm
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- Krüger, C W (författare)
- Dept. of Dental Medicine, Karolinska Institutet, Huddinge; Department of Oral and Maxillofacial Surgery, Eastmaninstitutet, Folktandvården Stockholm AB
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- Antovic, J P (författare)
- Karolinska Institutet
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- Naimi-Akbar, Aron (författare)
- Malmö universitet,Odontologiska fakulteten (OD),Dept. of Dental Medicine, Karolinska Institutet, Huddinge; Department of Oral and Maxillofacial Surgery, Eastmaninstitutet, Folktandvården Stockholm AB
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(creator_code:org_t)
- Elsevier, 2020
- 2020
- Engelska.
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Ingår i: British Journal of Oral & Maxillofacial Surgery. - : Elsevier. - 0266-4356 .- 1532-1940. ; 58:9, s. e33-e37
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- The purpose of this study was to identify thrombin-activatable fibrinolysis inhibitor (TAFI) in saliva and to investigate the correlation between TAFI levels in saliva and plasma. Subjects included were healthy adults without diseases or medication that could affect coagulation. Samples of stimulated saliva and blood samples were obtained from 33 subjects. Levels of TAFI in saliva and plasma were analysed. The association between levels of TAFI in saliva and plasma was calculated using linear regression. Low levels of TAFIa/TAFIai were found in most saliva samples but only one sample had levels that were above the lower limit of detection of the assay used. TAFI (proenzyme) was not found in saliva, so no correlations could be calculated. In this study there was no indication that there is TAFI present in secreted saliva. Either TAFIa/TAFIai in saliva were much lower than in plasma and under the detection limit of the assay used, or there was no TAFIa/TAFIai in the saliva tested.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Odontologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dentistry (hsv//eng)
Nyckelord
- Blood Coagulation
- Fibrinolysis
- Saliva
- TAFI
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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