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Oral function in pa...
Oral function in patients with myasthenia gravis
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- Donskov, A. O. (författare)
- Department of Neurology, Aarhus University Hospital, Aarhus, Region midt, Denmark
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- Shimada, A. (författare)
- Department of Geriatric Dentistry, Osaka Dental University, Osaka, Japan
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- Vinge, L. (författare)
- Department of Neurology, Aarhus University Hospital, Aarhus, Region midt, Denmark
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- Svensson, Peter (författare)
- Malmö universitet,Odontologiska fakulteten (OD),Section of Orofacial Pain and Jaw Function, Department of Dentistry and Oral Health, Aarhus University, Denmark,Scandinavian Center for Orofacial Neurosciences (SCON)
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- Andersen, H. (författare)
- Department of Neurology, Aarhus University Hospital, Aarhus, Region midt, Denmark
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(creator_code:org_t)
- 2021-06-29
- 2021
- Engelska.
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Ingår i: PeerJ. - : PeerJ Inc.. - 2167-8359. ; 9
- Relaterad länk:
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https://doi.org/10.7...
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https://mau.diva-por... (primary) (Raw object)
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https://doi.org/10.7...
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https://urn.kb.se/re...
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https://doi.org/10.7...
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Abstract
Ämnesord
Stäng
- Myasthenia Gravis (MG) is characterised by muscle weakness and increased fatigability. The aim of this pilot study was to investigate if patients with MG demonstrate different functional chewing patterns and report more complaints related to mastication as compared with healthy controls. Twelve patients (median 60 years Q1–Q3: 46–70) with generalised MG and nine healthy controls (median 57 years Q1–Q3: 55–63) participated. All participants underwent dental and oral examination and were asked to fill in a questionnaire concerning oral health. Static maximum bite force was measured with a bite force transducer, electromyography in the masseter, temporalis, and suprahyoid muscles were recorded, and jaw movement was tracked, during a 5-minute gum chewing test. The patients had more oral complaints (oral health impact profile total score 22.6 vs 7.5 P < 0.01) and had lower peak bite force than controls (18.8kgf (11.1;26.4) (95% CI) vs 29.5 kgf (21.6; 37.4) (P = 0.04)). In contrast, fatigability of the masticatory muscles, as defined by number of chewing cycles during the gum-chewing test, did not differ between patients and controls (P = 0.10). In conclusion, patients had more oral complaints and lower bite force than controls, but did not show significantly different functional chewing patterns. Future studies should aim at integrating measurement of peak force into functional tests. Attention should be given to oral complaints of patients with MG.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Odontologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dentistry (hsv//eng)
Nyckelord
- Mastication
- Myasthenia Gravis
- Oral function
- methotrexate
- prednisolone
- pyridostigmine
- adult
- arthralgia
- Article
- attention
- auditory stimulation
- bone density
- clinical article
- controlled study
- disease severity
- dysphagia
- electromyography
- endoscopy
- fatigue
- female
- grip strength
- health
- human
- jaw movement
- male
- masticatory muscle
- mouth disease
- muscle contraction
- muscle strength
- muscle weakness
- myalgia
- neuromuscular junction
- periodontal disease
- prevalence
- quality of life
- questionnaire
- temporomandibular joint
- temporomandibular joint disorder
- weakness
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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