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Randomized Clinical...
Randomized Clinical Trials on Deep Carious Lesions : 5-Year Follow-up
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- Bjørndal, Lars (författare)
- Department of Odontology, University of Copenhagen, Copenhagen, Denmark
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- Fransson, Helena (författare)
- Malmö högskola,Odontologiska fakulteten (OD)
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- Bruun, Gitte (författare)
- Department of Odontology, University of Copenhagen, Copenhagen, Denmark
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- Markvart, Merete (författare)
- Karolinska Institutet
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- Kjældgaard, Marianne (författare)
- Department of Oral Medicine, Karolinska Institute, Stockholm, Sweden
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- Näsman, Peggy (författare)
- Karolinska Institutet
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- Hedenbjörk-Lager, Anders (författare)
- Malmö högskola,Odontologiska fakulteten (OD)
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- Dige, Irene (författare)
- Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark
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- Thordrup, Marianne (författare)
- Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark
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(creator_code:org_t)
- 2017-04-14
- 2017
- Engelska.
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Ingår i: Journal of Dental Research. - : Sage Publications. - 0022-0345 .- 1544-0591. ; 96:7, s. 747-753
- Relaterad länk:
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http://journals.sage...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Deep caries presents a dilemma in terms of which treatment that will render an optimal prognosis by maintaining pulp vitality with absence of apical pathology. Previously, 2 randomized clinical trials were performed testing the short-term effects of stepwise carious tissue removal versus nonselective carious removal to hard dentin with or without pulp exposure. The aim of this article was to report the 5-y outcome on these previously treated patients having radiographically well-defined carious lesions extending into the pulpal quarter of the dentin but with a well-defined radiodense zone between the carious lesion and the pulp. In this long-term study, 239 of 314 (76.2%) patients were analyzed. The stepwise removal group had a significantly higher proportion of success (60.2%) at 5-y follow-up compared with the nonselective carious removal to hard dentin group (46.3%) ( P = 0.031) when pulp exposures per se were included as failures. Pulp exposure rate was significantly lower in the stepwise carious removal group (21.2% vs. 35.5%; P = 0.014). Irrespective of pulp exposure status, the difference (13.3%) was still significant when sustained pulp vitality without apical radiolucency and unbearable pain was considered (95% confidence interval, 3.1-26.3, P = 0.045). After pulp exposure, only 9% ( n = 4) of the analyzed patients were assessed as successful, indicating that the prognosis is highly dubious following conventional pulp-capping procedures (direct pulp capping or partial pulpotomy) in deep carious lesions in adults. In conclusion, the stepwise carious removal group had a significantly higher proportion of pulps with sustained vitality without apical radiolucency versus nonselective carious removal of deep carious lesions in adult teeth at 5-y follow-up (ClinicalTrials.gov NCT00187837 and NCT00187850).
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Odontologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dentistry (hsv//eng)
Nyckelord
- caries treatment
- clinical studies
- clinical outcomes
- dentin
- Endodontics
- operative dentistry
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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