Sökning: onr:"swepub:oai:DiVA.org:miun-17249" >
Soluble urokinase p...
Soluble urokinase plasminogen activator receptor in patients with abdominal aortic aneurysm
-
- Lindqvist, Markus (författare)
- Sundsvall Cty Hosp, Dept Clin Chem, SE-85186 Sundsvall, Sweden
-
- Wallinder, Jonas (författare)
- Department of Surgery, Sundsvall County Hospital, Sweden
-
- Henriksson, Anders E. (författare)
- Mittuniversitetet,Institutionen för tillämpad naturvetenskap och design (-2013)
-
(creator_code:org_t)
- Elsevier BV, 2012
- 2012
- Engelska.
-
Ingår i: Thrombosis Research. - : Elsevier BV. - 0049-3848 .- 1879-2472. ; 130:3, s. 511-513
- Relaterad länk:
-
https://urn.kb.se/re...
-
visa fler...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- Introduction: In the present study we investigated the impact of soluble urokinase plasminogen activator receptor (suPAR) as a biomarker in patients with abdominal aortic aneurysm (AAA) in relation to conventional inflammatory markers, aneurysm size, and rupture. Methods: suPAR and conventional inflammatory markers were measured in 119 patients with AAA and 36 controls without aneurysm matched by age, gender and smoking habit. Results: The results support earlier studies suggesting a state of activated inflammatory response in patients with nonruptured AAA as expressed by elevated CRP and IL-6 compared with the controls. In contrast, suPAR showed similar levels in patients with nonruptured AAA compared with the controls. Unexpectedly, all follow-up patients (n = 16) have significant (p<0.001) elevated suPAR levels three years postoperatively compared preoperatively. Conclusions: suPAR does not seem to be a useful biomarker in the AAA disease. The role of the postoperative elevation of suPAR needs to be further elucidated. (C) 2012 Elsevier Ltd. All rights reserved.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Nyckelord
- Soluble urokinase plasminogen activator receptor
- C-reactive protein
- Interleukin-6
- Aneurysm
- Aorta
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas