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|---|---|---|
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| 001 | oai:DiVA.org:miun-36187 | |
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| 008 | 190522s2019 | |||||||||||000 ||eng| | |
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| 024 | 7 | a https://doi.org/10.1007/s10654-019-00502-92 DOI |
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| 100 | 1 | a Middeldorp, Christel M.u Child Health Research Centre, University of Queensland, Brisbane QLD, Australia; Child and Youth Mental Health Service, Children’s Health Queensland Hospital and Health Service, Brisbane QLD, Australia; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands4 aut |
| 245 | 1 0 | a The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia :b design, results and future prospects |
| 264 | c 2019-03-18 | |
| 264 | 1 | b Springer Science and Business Media LLC,c 2019 |
| 338 | a electronic2 rdacarrier | |
| 500 | a Funding Agencies:European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant 721567 European Union's Horizon 2020 research and innovation programme 633595 733206 Sir Henry Dale Fellowship (Wellcome Trust) Sir Henry Dale Fellowship (Royal Society) WT104150 American Diabetes Association 1-17-PDF-077 Dutch Science Organization (ZonMW-VENI Grant) 916.14.023 Australian National Health and Medical Research Council Early Career Fellowship APP1104818 Gene-Diet Interactions in Obesity (GENDINOB) project National Institute of Health Research European Research Council 323195 SZ-245 50371-GLUCOSEGENES-FP7-IDEAS-ERC Children's Hospital of Philadelphia Endowed Chair in Genomic Research National Institute for Health Research (NIHR) Senior Investigator Award NF-SI-0611-10219 German Research Society, German Ministry of Education and Research American Diabetes Association (ADA) Pathway Program Accelerator Early Investigator Award 1-15-ACE-26 Helse Vest 23929 Bergen Forskningsstiftelse KG Jebsen Foundation University of Bergen Academy of Finland Research Professor program 265240 263278 University of Queensland Development Fellowship UQFEL1718945 Li Ka Shing Foundation WT-SSI/John Fell funds NIHR Biomedical Research Centre, Oxford Widenlife NIH 5P50HD028138-27 NHMRC Senior Reseach Fellowship APP1103623 Career development fellowship 20308 Wellcome Trust WT098395 WT098051 WT205915 098051 National Institute for Health Research Biomedical Research Centre at Great Ormond Street Hospital for Children NHS Foundation Trust and University College London European Union's Horizon 2020 research European Union FP7-IDEAS-ERC Advanced Grant (GEPIDIAB) ERC-AG -ERC-294785 European Union FP7-IDEAS-ERC innovation programme (DYNAhealth) H2020-PHC-2014-633595 CRUK C18281/A19169 NHMRC Practitioner Fellowship Grant APP1105807 European Regional Development Fund (ERDF) European Social Fund (ESF) Convergence Programme for Cornwall Isles of Scilly Diabetes Research and Wellness Foundation Non-Clinical Fellowship Agencia de Gestio d'Ajuts Universitaris i de Recerca (AGAUR), Generalitat de Catalunya 2015 FI_B 00636 ZonMW TOP 40-00812-98-11010 MRC Human Genetics Unit quinquennial programme "QTL in Health and Disease" Diabetes UK RD Lawrence fellowship 17/0005594 BBMRI-NL CP2013-50 Novo Nordisk Foundation 12955 Oak Foundation Fellowship European Research Council (ERC) KG Jebsen European Research Council under the European Union's Seventh Framework Programme (FP/2007-2013)/ERC Grant 669545 US National Institute of Health R01 DK10324 UK Medical Research Council MC_UU_00011/6 Wellcome Trust GWAS grant WT088806 NIHR Senior Investigator Award NF-SI-0611-10196 NIHR Biomedical Research Centre at University Hospitals Bristol NHS Foundation Trust and the University of Bristol UK Medical Research Council Unit MC_UU_12013_5 MC_UU_12013_4 University of Bristol NIHR Biomedical Research Centre (BRC) 202802/Z/16/Z WT 102215/2/13/2 CRUK Integrative Cancer Epidemiology Programme C18281/A19169 Netherlands Organization for Health Research and Development (NWO) ZonMw-VIDI 016.136.361 European Research Council Consolidator Grant ERC-2014-CoG-648916 Australian Research Council Future Fellowship FT130101709 NHMRC Senior Research Fellowship GNT1137714 Daniel B. Burke Endowed Chair for Diabetes Research Spinozapremie NWO-56-464-14192 Royal Netherlands Academy of Science Professor Award PAH/6635 NIHR NF-SI-0617-10090 Wellcome 090532 098381 203141 R01 HD056465 | |
| 520 | a The impact of many unfavorable childhood traits or diseases, such as low birth weight and mental disorders, is not limited to childhood and adolescence, as they are also associated with poor outcomes in adulthood, such as cardiovascular disease. Insight into the genetic etiology of childhood and adolescent traits and disorders may therefore provide new perspectives, not only on how to improve wellbeing during childhood, but also how to prevent later adverse outcomes. To achieve the sample sizes required for genetic research, the Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia were established. The majority of the participating cohorts are longitudinal population-based samples, but other cohorts with data on early childhood phenotypes are also involved. Cohorts often have a broad focus and collect(ed) data on various somatic and psychiatric traits as well as environmental factors. Genetic variants have been successfully identified for multiple traits, for example, birth weight, atopic dermatitis, childhood BMI, allergic sensitization, and pubertal growth. Furthermore, the results have shown that genetic factors also partly underlie the association with adult traits. As sample sizes are still increasing, it is expected that future analyses will identify additional variants. This, in combination with the development of innovative statistical methods, will provide detailed insight on the mechanisms underlying the transition from childhood to adult disorders. Both consortia welcome new collaborations. Policies and contact details are available from the corresponding authors of this manuscript and/or the consortium websites. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskap0 (SwePub)3032 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciences0 (SwePub)3032 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Reproduktionsmedicin och gynekologi0 (SwePub)302202 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Obstetrics, Gynaecology and Reproductive Medicine0 (SwePub)302202 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicin0 (SwePub)3022 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicine0 (SwePub)3022 hsv//eng |
| 653 | a Genetics | |
| 653 | a Consortium | |
| 653 | a Childhood traits and disorders | |
| 653 | a Longitudinal | |
| 700 | 1 | a Mahajan, Anubha4 aut |
| 700 | 1 | a Horikoshi, Momoko4 aut |
| 700 | 1 | a Robertson, Neil R.4 aut |
| 700 | 1 | a Beaumont, Robin N.4 aut |
| 700 | 1 | a Bradfield, Jonathan P.4 aut |
| 700 | 1 | a Bustamante, Mariona4 aut |
| 700 | 1 | a Cousminer, Diana L.4 aut |
| 700 | 1 | a Day, Felix R.4 aut |
| 700 | 1 | a De Silva, N. Maneka4 aut |
| 700 | 1 | a Guxens, Monica4 aut |
| 700 | 1 | a Mook-Kanamori, Dennis O.4 aut |
| 700 | 1 | a St Pourcain, Beate4 aut |
| 700 | 1 | a Warrington, Nicole M.4 aut |
| 700 | 1 | a Adair, Linda S.4 aut |
| 700 | 1 | a Ahlqvist, Emmau Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups4 aut0 (Swepub:lu)infl-eah |
| 700 | 1 | a Ahluwalia, Tarunveer S.4 aut |
| 700 | 1 | a Almgren, Peter4 aut |
| 700 | 1 | a Ang, Wei4 aut |
| 700 | 1 | a Atalay, Mustafa4 aut |
| 700 | 1 | a Auvinen, Juha4 aut |
| 700 | 1 | a Bartels, Meike4 aut |
| 700 | 1 | a Beckmann, Jacques S.4 aut |
| 700 | 1 | a Bilbao, Jose Ramon4 aut |
| 700 | 1 | a Bond, Tom4 aut |
| 700 | 1 | a Borja, Judith B.4 aut |
| 700 | 1 | a Cavadino, Alana4 aut |
| 700 | 1 | a Charoen, Pimphen4 aut |
| 700 | 1 | a Chen, Zhanghua4 aut |
| 700 | 1 | a Coin, Lachlan4 aut |
| 700 | 1 | a Cooper, Cyrus4 aut |
| 700 | 1 | a Curtin, John A.4 aut |
| 700 | 1 | a Custovic, Adnan4 aut |
| 700 | 1 | a Das, Shikta4 aut |
| 700 | 1 | a Davies, Gareth E.4 aut |
| 700 | 1 | a Dedoussis, George V.4 aut |
| 700 | 1 | a Duijts, Liesbeth4 aut |
| 700 | 1 | a Eastwood, Peter R.4 aut |
| 700 | 1 | a Eliasen, Anders U.4 aut |
| 700 | 1 | a Elliott, Paul4 aut |
| 700 | 1 | a Eriksson, Johan G.4 aut |
| 700 | 1 | a Estivill, Xavier4 aut |
| 700 | 1 | a Fadista, Joao4 aut |
| 700 | 1 | a Fedko, Iryna O.4 aut |
| 700 | 1 | a Frayling, Timothy M.4 aut |
| 700 | 1 | a Gaillard, Romy4 aut |
| 700 | 1 | a Gauderman, W. James4 aut |
| 700 | 1 | a Geller, Frank4 aut |
| 700 | 1 | a Gilliland, Frank4 aut |
| 700 | 1 | a Gilsanz, Vincente4 aut |
| 700 | 1 | a Granell, Raquel4 aut |
| 700 | 1 | a Grarup, Niels4 aut |
| 700 | 1 | a Groop, Leifu Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups,University of Helsinki4 aut0 (Swepub:lu)endo-lgr |
| 700 | 1 | a Hadley, Dexter4 aut |
| 700 | 1 | a Hakonarson, Hakonu Karolinska Institutet4 aut |
| 700 | 1 | a Hansen, Torben4 aut |
| 700 | 1 | a Hartman, Catharina A.4 aut |
| 700 | 1 | a Hattersley, Andrew T.4 aut |
| 700 | 1 | a Hayes, M. Geoffrey4 aut |
| 700 | 1 | a Hebebrand, Johannes4 aut |
| 700 | 1 | a Heinrich, Joachim4 aut |
| 700 | 1 | a Helgeland, Oyvind4 aut |
| 700 | 1 | a Henders, Anjali K.4 aut |
| 700 | 1 | a Henderson, John4 aut |
| 700 | 1 | a Henriksen, Tine B.4 aut |
| 700 | 1 | a Hirschhorn, Joel N.4 aut |
| 700 | 1 | a Hivert, Marie-France4 aut |
| 700 | 1 | a Hocher, Berthold4 aut |
| 700 | 1 | a Holloway, John W.4 aut |
| 700 | 1 | a Holt, Patrick4 aut |
| 700 | 1 | a Hottenga, Jouke-Jan4 aut |
| 700 | 1 | a Hypponen, Elina4 aut |
| 700 | 1 | a Iniguez, Carmen4 aut |
| 700 | 1 | a Johansson, Stefan4 aut |
| 700 | 1 | a Jugessur, Astanand4 aut |
| 700 | 1 | a Kahonen, Mika4 aut |
| 700 | 1 | a Kalkwarf, Heidi J.4 aut |
| 700 | 1 | a Kaprio, Jaakko4 aut |
| 700 | 1 | a Karhunen, Ville4 aut |
| 700 | 1 | a Kemp, John P.4 aut |
| 700 | 1 | a Kerkhof, Marjan4 aut |
| 700 | 1 | a Koppelman, Gerard H.4 aut |
| 700 | 1 | a Korner, Antje4 aut |
| 700 | 1 | a Kotecha, Sailesh4 aut |
| 700 | 1 | a Kreiner-Moller, Eskil4 aut |
| 700 | 1 | a Kulohoma, Benard4 aut |
| 700 | 1 | a Kumar, Ashish4 aut |
| 700 | 1 | a Kutalik, Zoltan4 aut |
| 700 | 1 | a Lahti, Jari4 aut |
| 700 | 1 | a Lappe, Joan M.4 aut |
| 700 | 1 | a Larsson, Henrik,d 1975-u Örebro universitet,Institutionen för medicinska vetenskaper,Univ Penn, Perelman Sch Med, Dept Pediat, Philadelphia, PA 19104 USA.;Univ Groningen, Univ Med Ctr Groningen, Dept Psychiat, Groningen, Netherlands.;Orebro Univ, Sch Med Sci, Orebro, Sweden.;Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden.;Univ Oxford, Oxford Ctr Diabet Endocrinol & Metab, Oxford OX3 7LE, England.;RIKEN, Ctr Integrat Med Sci, Lab Endocrinol Metab & Kidney Dis, Yokohama, Kanagawa 2300045, Japan.;Orebro Univ, Sch Med Sci, Orebro, Sweden.;Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden.4 aut0 (Swepub:oru)hiln |
| 700 | 1 | a Lehtimaki, Terho4 aut |
| 700 | 1 | a Lewin, Alexandra M.4 aut |
| 700 | 1 | a Li, Jin4 aut |
| 700 | 1 | a Lichtenstein, Paulu Karolinska Institutet4 aut |
| 700 | 1 | a Lindgren, Cecilia M.4 aut |
| 700 | 1 | a Lindi, Virpi4 aut |
| 700 | 1 | a Linneberg, Allan4 aut |
| 700 | 1 | a Liu, Xueping4 aut |
| 700 | 1 | a Liu, Jun4 aut |
| 700 | 1 | a Lowe, William L., Jr.4 aut |
| 700 | 1 | a Lundstrom, Sebastian4 aut |
| 700 | 1 | a Lyytikainen, Leo-Pekka4 aut |
| 700 | 1 | a Ma, Ronald C. W.4 aut |
| 700 | 1 | a Mace, Aurelien4 aut |
| 700 | 1 | a Magi, Reedik4 aut |
| 700 | 1 | a Magnus, Per4 aut |
| 700 | 1 | a Mamun, Abdullah A.4 aut |
| 700 | 1 | a Mannikko, Minna4 aut |
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| 700 | 1 | a Mbarek, Hamdi4 aut |
| 700 | 1 | a McCarthy, Nina S.4 aut |
| 700 | 1 | a Medland, Sarah E.4 aut |
| 700 | 1 | a Melbye, Mads4 aut |
| 700 | 1 | a Melen, Eriku Karolinska Institutet4 aut |
| 700 | 1 | a Mohlke, Karen L.4 aut |
| 700 | 1 | a Monnereau, Claire4 aut |
| 700 | 1 | a Morgen, Camilla S.4 aut |
| 700 | 1 | a Morris, Andrew P.4 aut |
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| 700 | 1 | a Myhre, Ronny4 aut |
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| 700 | 1 | a Nivard, Michel G.4 aut |
| 700 | 1 | a Nohr, Ellen A.4 aut |
| 700 | 1 | a Nolte, Ilja M.4 aut |
| 700 | 1 | a Ntalla, Ioanna4 aut |
| 700 | 1 | a O'Reilly, Paul4 aut |
| 700 | 1 | a Oberfield, Sharon E.4 aut |
| 700 | 1 | a Oken, Emily4 aut |
| 700 | 1 | a Oldehinkel, Albertine J.4 aut |
| 700 | 1 | a Pahkala, Katja4 aut |
| 700 | 1 | a Palviainen, Teemu4 aut |
| 700 | 1 | a Panoutsopoulou, Kalliope4 aut |
| 700 | 1 | a Pedersen, Oluf4 aut |
| 700 | 1 | a Pennell, Craig E.4 aut |
| 700 | 1 | a Pershagen, Goranu Karolinska Institutet4 aut |
| 700 | 1 | a Pitkanen, Niina4 aut |
| 700 | 1 | a Plomin, Robert4 aut |
| 700 | 1 | a Power, Christine4 aut |
| 700 | 1 | a Prasad, Rashmiu Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups4 aut0 (Swepub:lu)med-rpa |
| 700 | 1 | a Prokopenko, Inga4 aut |
| 700 | 1 | a Pulkkinen, Lea4 aut |
| 700 | 1 | a Raikkonen, Katri4 aut |
| 700 | 1 | a Raitakari, Olli T.4 aut |
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| 700 | 1 | a Rose, Richard J.4 aut |
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| 700 | 1 | a Sorensen, Thorkild I. A.4 aut |
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| 700 | 1 | a Steegers, Eric A. P.4 aut |
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| 700 | 1 | a Vrijkotte, Tanja G. M.4 aut |
| 700 | 1 | a Vuoksimaa, Eero4 aut |
| 700 | 1 | a Wang, Carol A.4 aut |
| 700 | 1 | a Watkins, William J.4 aut |
| 700 | 1 | a Wichmann, H-Erich4 aut |
| 700 | 1 | a Willemsen, Gonneke4 aut |
| 700 | 1 | a Williams, Gail M.4 aut |
| 700 | 1 | a Wilson, James F.4 aut |
| 700 | 1 | a Wray, Naomi R.4 aut |
| 700 | 1 | a Xu, Shujing4 aut |
| 700 | 1 | a Xu, Cheng-Jian4 aut |
| 700 | 1 | a Yaghootkar, Hanieh4 aut |
| 700 | 1 | a Yi, Luu Karolinska Institutet4 aut |
| 700 | 1 | a Zafarmand, Mohammad Hadi4 aut |
| 700 | 1 | a Zeggini, Eleftheria4 aut |
| 700 | 1 | a Zemel, Babette S.4 aut |
| 700 | 1 | a Hinney, Anke4 aut |
| 700 | 1 | a Lakka, Timo A.4 aut |
| 700 | 1 | a Whitehouse, Andrew J. O.4 aut |
| 700 | 1 | a Sunyer, Jordi4 aut |
| 700 | 1 | a Widen, Elisabeth E.4 aut |
| 700 | 1 | a Feenstra, Bjarke4 aut |
| 700 | 1 | a Sebert, Sylvain4 aut |
| 700 | 1 | a Jacobsson, Bo,d 1960u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för obstetrik och gynekologi,Institute of Clinical Sciences, Department of Obstetrics and Gynecology4 aut0 (Swepub:gu)xjacbo |
| 700 | 1 | a Njolstad, Pal R.4 aut |
| 700 | 1 | a Stoltenberg, Camilla4 aut |
| 700 | 1 | a Smith, George Davey4 aut |
| 700 | 1 | a Lawlor, Debbie A.4 aut |
| 700 | 1 | a Paternoster, Lavinia4 aut |
| 700 | 1 | a Timpson, Nicholas J.4 aut |
| 700 | 1 | a Ong, Ken K.4 aut |
| 700 | 1 | a Bisgaard, Hans4 aut |
| 700 | 1 | a Bonnelykke, Klaus4 aut |
| 700 | 1 | a Jaddoe, Vincent W. V.4 aut |
| 700 | 1 | a Tiemeier, Henning4 aut |
| 700 | 1 | a Jarvelin, Marjo-Riitta4 aut |
| 700 | 1 | a Evans, David M.4 aut |
| 700 | 1 | a Perry, John R. B.4 aut |
| 700 | 1 | a Grant, Struan F. A.4 aut |
| 700 | 1 | a Boomsma, Dorret I.4 aut |
| 700 | 1 | a Freathy, Rachel M.4 aut |
| 700 | 1 | a McCarthy, Mark I.u University of Oxford4 aut |
| 700 | 1 | a Felix, Janine F.4 aut |
| 700 | 1 | a Tiemeier, Hen-Ningu Univ Leipzig, Pediat Res Ctr, Dept Womens & Child Hlth, Leipzig, Germany; Univ Leipzig, IFB Adipos Dis, Leipzig, Germany; Univ N Carolina, Dept Genet, Chapel Hill NC, USA; Leiden Univ, Dept Clin Epidemiol, Med Ctr, Leiden, Netherlands; Erasmus MC, Child & Adolescent Psychiat, Rotterdam, Netherlands; Harvard Univ, Social & Behav Sci, Harvard TH Chan Sch Publ Hlth, Boston MA, USA4 aut |
| 710 | 2 | a Child Health Research Centre, University of Queensland, Brisbane QLD, Australia; Child and Youth Mental Health Service, Children’s Health Queensland Hospital and Health Service, Brisbane QLD, Australia; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlandsb Genomik, diabetes och endokrinologi4 org |
| 710 | 2 | a Early Growth Genetics (EGG) consortium |
| 773 | 0 | t European Journal of Epidemiologyd : Springer Science and Business Media LLCg 34:3, s. 279-300q 34:3<279-300x 0393-2990x 1573-7284 |
| 856 | 4 | u https://miun.diva-portal.org/smash/get/diva2:1317328/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
| 856 | 4 | u https://link.springer.com/content/pdf/10.1007/s10654-019-00502-9.pdf |
| 856 | 4 | u https://doi.org/10.1007/s10654-019-00502-9y Fulltext |
| 856 | 4 | u http://dx.doi.org/10.1007/s10654-019-00502-9x freey FULLTEXT |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-36187 |
| 856 | 4 8 | u https://doi.org/10.1007/s10654-019-00502-9 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-73963 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:140709159 |
| 856 | 4 8 | u https://lup.lub.lu.se/record/ece0f922-687a-4202-bb39-d805c5ca57bd |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/278722 |
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