Sökning: onr:"swepub:oai:DiVA.org:miun-51108" >
Edge-illumination s...
Edge-illumination spectral phase-contrast tomography
-
- Brombal, Luca (författare)
- Univ Trieste, Dept Phys, Via A Valerio 2, I-34127 Trieste, Italy.;SIMT, I-34127 Empoli, Italy.
-
- Arfelli, Fulvia (författare)
- Univ Trieste, Dept Phys, Via A Valerio 2, I-34127 Trieste, Italy.;SIMT, I-34127 Empoli, Italy.
-
- Brun, Francesco (författare)
- SIMT, I-34127 Empoli, Italy.;Univ Trieste, Dept Engn & Architecture, Via A Valerio 10, Trieste, Italy.
-
visa fler...
-
- Di Trapani, Vittorio (författare)
- Univ Trieste, Dept Phys, Via A Valerio 2, I-34127 Trieste, Italy.
-
- Endrizzi, Marco (författare)
- UCL, Dept Med Phys & Biomed Engn, Gower St, London GWC1E 6BT, England.
-
- Menk, Ralf H., Adjungerad Professor (författare)
- Mittuniversitetet,Institutionen för data- och elektroteknik (2023-),SIMT, I-34127 Empoli, Italy.;Elettra Sincrotrone Trieste SCpA, Basovizza Trieste, Italy.
-
- Perion, Paola (författare)
- Univ Trieste, Dept Phys, Via A Valerio 2, I-34127 Trieste, Italy.;SIMT, I-34127 Empoli, Italy.
-
- Rigon, Luigi (författare)
- Univ Trieste, Dept Phys, Via A Valerio 2, I-34127 Trieste, Italy.;SIMT, I-34127 Empoli, Italy.
-
- Saccomano, Mara (författare)
- Helmholtz Zentrum Munchen, Helmholtz Pioneer Campus, Ingolstadter Landstr 1, D-85764 Neuherberg, Germany.
-
- Tromba, Giuliana (författare)
- Elettra Sincrotrone Trieste SCpA, Basovizza Trieste, Italy.
-
- Olivo, Alessandro (författare)
- UCL, Dept Med Phys & Biomed Engn, Gower St, London GWC1E 6BT, England.
-
visa färre...
-
Univ Trieste, Dept Phys, Via A Valerio 2, I-34127 Trieste, Italy;SIMT, I-34127 Empoli, Italy. SIMT, I-34127 Empoli, Italy.;Univ Trieste, Dept Engn & Architecture, Via A Valerio 10, Trieste, Italy. (creator_code:org_t)
- IOP Publishing, 2024
- 2024
- Engelska.
-
Ingår i: Physics in Medicine and Biology. - : IOP Publishing. - 0031-9155 .- 1361-6560. ; 69:7
- Relaterad länk:
-
https://doi.org/10.1...
-
visa fler...
-
https://miun.diva-po... (primary) (Raw object)
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- Following the rapid, but independent, diffusion of x-ray spectral and phase-contrast systems, this work demonstrates the first combination of spectral and phase-contrast computed tomography (CT) obtained by using the edge-illumination technique and a CdTe small-pixel (62 mu m) spectral detector. A theoretical model is introduced, starting from a standard attenuation-based spectral decomposition and leading to spectral phase-contrast material decomposition. Each step of the model is followed by quantification of accuracy and sensitivity on experimental data of a test phantom containing different solutions with known concentrations. An example of a micro CT application (20 mu m voxel size) on an iodine-perfused ex vivo murine model is reported. The work demonstrates that spectral-phase contrast combines the advantages of spectral imaging, i.e. high-Z material discrimination capability, and phase-contrast imaging, i.e. soft tissue sensitivity, yielding simultaneously mass density maps of water, calcium, and iodine with an accuracy of 1.1%, 3.5%, and 1.9% (root mean square errors), respectively. Results also show a 9-fold increase in the signal-to-noise ratio of the water channel when compared to standard spectral decomposition. The application to the murine model revealed the potential of the technique in the simultaneous 3D visualization of soft tissue, bone, and vasculature. While being implemented by using a broad spectrum (pink beam) at a synchrotron radiation facility (Elettra, Trieste, Italy), the proposed experimental setup can be readily translated to compact laboratory systems including conventional x-ray tubes.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
Nyckelord
- x-ray phase-contrast imaging
- spectral imaging
- edge illumination
- photon-counting detector
- x-ray tomography
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Brombal, Luca
-
Arfelli, Fulvia
-
Brun, Francesco
-
Di Trapani, Vitt ...
-
Endrizzi, Marco
-
Menk, Ralf H., A ...
-
visa fler...
-
Perion, Paola
-
Rigon, Luigi
-
Saccomano, Mara
-
Tromba, Giuliana
-
Olivo, Alessandr ...
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Radiologi och bi ...
- Artiklar i publikationen
-
Physics in Medic ...
- Av lärosätet
-
Mittuniversitetet