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Associations Between Attention Deficit Hyperactivity Disorder Symptom Dimensions and Disordered Eating Symptoms in Adolescence : A Population-Based Twin Study
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- Yilmaz, Zeynep (författare)
- National Centre for Register-Based Research, Aarhus BSS, Aarhus University, Aarhus, Denmark; Department of Biomedicine, Aarhus University, Aarhus, Denmark; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
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- Quattlebaum, Mary J. (författare)
- Department of Psychology, University of South Carolina, Columbia, SC, USA
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- Pawar, Pratiksha S. (författare)
- Dr. D. Y. Patil Biotechnology and Bioinformatics Institute, Dr. D. Y. Patil Vidyapeeth, Pune, India
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- Thornton, Laura M. (författare)
- Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
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- Bulik, Cynthia M. (författare)
- Karolinska Institutet
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- Javaras, Kristin N. (författare)
- Department of Psychiatry, Harvard Medical School, Boston, MA, USA; Division of Women's Mental Health, McLean Hospital, Belmont, MA, USA
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- Yao, Shuyang (författare)
- Karolinska Institutet
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- Lichtenstein, Paul (författare)
- Karolinska Institutet
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- Larsson, Henrik, 1975- (författare)
- Karolinska Institutet,Örebro universitet,Institutionen för medicinska vetenskaper,Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
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- Baker, Jessica H. (författare)
- Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
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(creator_code:org_t)
- 2022-12-09
- 2023
- Engelska.
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Ingår i: Behavior Genetics. - : Springer. - 0001-8244 .- 1573-3297. ; 53:2, s. 143-153
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Although bivariate associations between attention-deficit/hyperactivity disorder (ADHD) and eating disorders in adolescent girls and boys have been previously identified, the mechanistic link underlying the symptom-level associations remains unclear. We evaluated shared genetic and environmental influences on ADHD symptoms and disordered eating in 819 female and 756 male twins from the Swedish TCHAD cohort using bivariate models. Common additive genetic and unique environmental effects accounted for majority of ADHD and disordered eating associations in a differential manner. For girls, the strongest genetic correlation was observed for cognitive/inattention problems-bulimia (0.54), with genetic factors accounting for 67% of the phenotypic correlation. For boys, the strongest genetic correlations were observed for conduct problems-bulimia and hyperactivity-bulimia (~ 0.54), accounting for 83% and 95% of the phenotypic correlation, respectively. As per our findings, the risk of comorbidity and shared genetics highlights the need for preventative measures and specialized treatment for ADHD and disordered eating in both sexes.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
Nyckelord
- Attention-deficit/hyperactivity disorder
- Disordered eating
- Genetics
- Population cohort
- Sex differences
- Symptom-level associations
- Twin study
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- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Yilmaz, Zeynep
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Quattlebaum, Mar ...
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Pawar, Pratiksha ...
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Thornton, Laura ...
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Bulik, Cynthia M ...
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Javaras, Kristin ...
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visa fler...
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Yao, Shuyang
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Lichtenstein, Pa ...
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Larsson, Henrik, ...
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Baker, Jessica H ...
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Psykiatri
- Artiklar i publikationen
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Behavior Genetic ...
- Av lärosätet
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Örebro universitet
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Karolinska Institutet