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Comprehensive mappi...
Comprehensive mapping review of real-world evidence publications focusing on targeted therapies in solid tumors : A collaborative work from ESMO real-world data and Digital Health Working Group
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- Pellat, A. (författare)
- Gastroenterology and digestive oncology Department, Hôpital Cochin, Paris, France
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- Grinda, T. (författare)
- Medical Oncology Dept., Institut Gustave Roussy, Villejuif, France
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- Prelaj, A. (författare)
- Department of Medical Oncology, Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan, Italy
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- Cresta, P. (författare)
- Medical Oncology Dept., VHIO - Vall d’Hebron Institute of Oncology, Barcelona, Spain
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- Valachis, A, 1984- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Dpt. of Oncology
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- Zerdes, I. (författare)
- Karolinska Institutet
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- Branco, D. Martins (författare)
- Academic Trials Promoting Team (ATPT), Université Libre de Bruxelles (ULB), Hôpital Universitaire de Bruxelles (HUB), Institut Jules Bordet, Brussels, Belgium
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- Provenzano, L. (författare)
- Department of Medical Oncology, Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan, Italy
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- Spagnoletti, A. (författare)
- Department of Medical Oncology, Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan, Italy
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- Marta, G. Nader (författare)
- Academic Trials Promoting Team (ATPT), Université Libre de Bruxelles (ULB), Hôpital Universitaire de Bruxelles (HUB), Institut Jules Bordet, Brussels, Belgium
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- Wilson, B. (författare)
- Department of Oncology, Queen's University, Kingston ON, Canada
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- Montemurro, F. (författare)
- Investigative Clinical Oncology dept., IRCCS - Istituto di Candiolo - FPO, Turin, Italy
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- Castelo-Branco, L. (författare)
- Scientific and Medical Division, ESMO - European Society for Medical Oncology, Lugano, Switzerland
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- Pentheroudakis, G. (författare)
- Scientific and Medical Division, ESMO - European Society for Medical Oncology, Lugano, Switzerland
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- Delaloge, S. (författare)
- Breast Oncology Department, Institut Gustave Roussy, Villejuif, France
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- Koopman, M. (författare)
- Medical Oncology Department, UMC - University Medical Center Utrecht, Utrecht, Netherlands
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Gastroenterology and digestive oncology Department, Hôpital Cochin, Paris, France Medical Oncology Dept, Institut Gustave Roussy, Villejuif, France (creator_code:org_t)
- Elsevier, 2023
- 2023
- Engelska.
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Ingår i: Annals of Oncology. - : Elsevier. - 0923-7534 .- 1569-8041. ; 34:Suppl. 2, s. S925-S925
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
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- Background: A growing body of real-world evidence (RWE) aims to better reflect outcomes of cancer patients treated in real-world settings. We aimed to conduct a first comprehensive mapping review of the RWE produced over the past 3 years in terms of tumor type, treatment strategies, setting, and data sources, focusing on targeted therapies (TT) in solid tumors.Methods: We conducted a systematic review in PubMed of RWE studies published between 01/2020 and 12/2022. We identified non-interventional studies using observational data, focusing on solid tumors exposure to targeted therapies, excluding immunotherapies. Abstract and full-text screening were performed by 11 independent reviewers.Results: A total of 7,774 publications were retrieved with 1,251 considered eligible and extracted. The number of publications per year progressively increased during this period (328 in 2020; 421 in 2021; 502 in 2022). Most studies (50%) were performed in Asia, followed by Europe (25%) and North America (17%). Only 8% of studies had patients treated in more than one country. Treatment effectiveness and safety were assessed in 71% and 42% of studies respectively. Main data sources were medical records.Conclusions: RWE publications on TT for solid tumors are heterogeneous and mostly rely on retrospective data such as medical records. Population-based and international studies are rare. Collaborative efforts towards international representativeness and the use of routinely collected and/or standardized data sources must be encouraged to increase the relevance and future quality of publications and their potential impact on oncology practice.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Publikations- och innehållstyp
- vet (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Pellat, A.
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Grinda, T.
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Prelaj, A.
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Cresta, P.
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Valachis, A, 198 ...
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Zerdes, I.
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visa fler...
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Branco, D. Marti ...
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Provenzano, L.
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Spagnoletti, A.
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Marta, G. Nader
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Wilson, B.
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Montemurro, F.
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Castelo-Branco, ...
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Pentheroudakis, ...
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Delaloge, S.
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Koopman, M.
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Cancer och onkol ...
- Artiklar i publikationen
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Annals of Oncolo ...
- Av lärosätet
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Örebro universitet
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Karolinska Institutet