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Sökning: onr:"swepub:oai:DiVA.org:oru-110379" > COVID-19 breakthrou...

COVID-19 breakthrough infections in type 1 diabetes mellitus : a cross-sectional study by the COVID-19 Vaccination in Autoimmune Diseases (COVAD) Group

Panchawagh, Suhrud (författare)
Smt Kashibai Navale Medical College, Pune, India
Ravichandran, Naveen (författare)
Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
Barman, Bhupen (författare)
Department of Medicine, All India Institute of Medical Science (AIIMS), Guwahati, India
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Nune, Arvind (författare)
Department of Rheumatology, Southport and Ormskirk Hospital NHS Trust, Southport, UK
Javaid, Mahnoor (författare)
Medical College, The Aga Khan University, Karachi, Pakistan
Gracia-Ramos, Abraham Edgar (författare)
Department of Internal Medicine, General Hospital, National Medical Center "La Raza", Instituto Mexicano del Seguro Social, Av. Jacaranda S/N, Col. La Raza, C.P. 02990, Del. AzcapotzalcoMexico City, Mexico
Day, Jessica (författare)
Department of Rheumatology, Royal Melbourne Hospital, Parkville, VIC, Australia; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia
Joshi, Mrudula (författare)
Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals, Pune, India
Kuwana, Masataka (författare)
Department of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, Japan
Saha, Sreoshy (författare)
Mymensingh Medical College, Mymensingh, Bangladesh
Pande, Arunkumar R. (författare)
LEDTC Clinic, Uttar Pradesh, Gomti Nagar, Lucknow, India
Caballero-Uribe, Carlo Vinicio (författare)
Department of Medicine, Hospital Universidad del Norte, Barranquilla, Atlantico, Colombia
Velikova, Tsvetelina (författare)
Medical Faculty, Sofia University St. Kliment Ohridski, 1 Kozyak Str., 1407, Sofia, Bulgaria
Parodis, Ioannis, 1981- (författare)
Örebro universitet,Institutionen för medicinska vetenskaper,Division of Rheumatology, Department of Medicine Solna, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden; Department of Rheumatology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden
Knitza, Johannes (författare)
Medizinische Klinik 3-Rheumatologie und Immunologie, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Deutschland
Kadam, Esha (författare)
Seth Gordhandhas Sunderdas Medical College and King Edwards Memorial Hospital, Mumbai, Maharashtra, India
Tan, Ai Lyn (författare)
NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust, Leeds, UK; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK
Shinjo, Samuel Katsuyuki (författare)
Division of Rheumatology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, São Paulo, Brazil
Boro, Hiya (författare)
Department of Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, India
Aggarwal, Rohit (författare)
Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Agarwal, Vikas (författare)
Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
Chatterjee, Tulika (författare)
Center for Outcomes Research, Department of Internal Medicine, University of Illinois College of Medicine Peoria, Peoria, IL, USA
Gupta, Latika (författare)
Department of Rheumatology, Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, WV10 0QP, UK; Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK; Department of Rheumatology, City Hospital, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK
COVAD Study Group, - (bidragsgivare)
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 (creator_code:org_t)
Springer, 2024
2024
Engelska.
Ingår i: Rheumatology International. - : Springer. - 0172-8172 .- 1437-160X. ; 44:1, s. 73-80
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • To investigate the frequency, profile, and severity of COVID-19 breakthrough infections (BI) in patients with type I diabetes mellitus (T1DM) compared to healthy controls (HC) after vaccination. The second COVID-19 Vaccination in Autoimmune Diseases (COVAD-2) survey is a multinational cross-sectional electronic survey which has collected data on patients suffering from various autoimmune diseases including T1DM. We performed a subgroup analysis on this cohort to investigate COVID-19 BI characteristics in patients with T1DM. Logistic regression with propensity score matching analysis was performed. A total of 9595 individuals were included in the analysis, with 100 patients having T1DM. Among the fully vaccinated cohort, 16 (16%) T1DM patients had one BI and 2 (2%) had two BIs. No morbidities or deaths were reported, except for one patient who required hospitalization with oxygen without admission to intensive care. The frequency, clinical features, and severity of BIs were not significantly different between T1DM patients and HCs after adjustment for confounding factors. Our study did not show any statistically significant differences in the frequency, symptoms, duration, or critical care requirements between T1DM and HCs after COVID-19 vaccination. Further research is needed to identify factors associated with inadequate vaccine response in patients with BIs, especially in patients with autoimmune diseases.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)

Nyckelord

Breakthrough infections
COVID-19
Survey
Type 1 diabetes mellitus
Vaccine

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