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Substance use-relat...
Substance use-related problems in mild intellectual disability : A Swedish nationwide population-based cohort study with sibling comparison
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- Påhlsson-Notini, Andreas (författare)
- Department of Medical, Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden,Karolinska Institutet, Stockholm, Sweden
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- Liu, Shengxin (författare)
- Department of Medical, Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden,Karolinska Institutet, Stockholm, Sweden
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- Tideman, Magnus, 1959- (författare)
- Högskolan i Halmstad,Akademin för hälsa och välfärd
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- Latvala, Antti (författare)
- Department of Medical, Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden; Institute of Criminology and Legal Policy, University of Helsinki, Helsinki, Finland,Karolinska Institutet, Stockholm, Sweden; University of Helsinki, Helsinki, Finland
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- Serlachius, Eva (författare)
- Karolinska Institutet
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- Larsson, Henrik, 1975- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Department of Medical, Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden,Karolinska Institutet, Stockholm, Sweden; Örebro University, Örebro, Sweden
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- Hirvikoski, Tatja (författare)
- Department of Women's and Children's Health, Pediatric Neuropsychiatry Unit Center for Neurodevelopmental Disorders at Karolinska Institutet, Karolinska Institutet, Stockholm, Sweden; Habilitation and Health, Stockholm Health Care Services, Stockholm, Sweden; Center for Psychiatry Research, Stockholm, Sweden
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- Taylor, Mark J. (författare)
- Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden,Karolinska Institutet, Stockholm, Sweden
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- Kuja-Halkola, Ralf (författare)
- Karolinska Institutet
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- Lichtenstein, Paul (författare)
- Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden,Karolinska Institutet, Stockholm, Sweden
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- Butwicka, Agnieszka (författare)
- Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden; Division of Mental Health Services, Akershus University Hospital and Institute of Clinical Medicine University of Oslo, Oslo, Norway; Department of Biostatistics and Translational Medicine, Medical University of Lodz, Lodz, Poland,Karolinska Institutet, Stockholm, Sweden; Akershus University Hospital, Lørenskog, Norway; Medical University of Lodz, Lodz, Poland
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(creator_code:org_t)
- Chichester : John Wiley & Sons, 2024
- 2024
- Engelska.
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Ingår i: JCPP Advances. - Chichester : John Wiley & Sons. - 2692-9384. ; 4:2
- Relaterad länk:
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- BACKGROUND: Evidence for substance use-related problems in individuals with mild intellectual disability is sparse and mainly limited to selected psychiatric populations. We evaluated the risk of substance use-related problems in individuals with mild intellectual disability compared to the general population. Additionally, we have performed secondary sibling comparison analyses to account for familial confounding.METHODS: We conducted a population-based cohort study of individuals born in Sweden between 1973 and 2003. A total of 18,307 individuals with mild intellectual disability were compared to 915,350 reference individuals from the general population and 18,996 full siblings of individuals with mild intellectual disability. Information on mild intellectual disability and substance use-related problems was obtained from several Swedish national and regional school and healthcare registers. Substance use-related problems were measured via corresponding diagnostic and legal codes and included alcohol use disorder, drug use disorder, alcohol-related somatic disease, conviction for a substance-related crime, and substance-related death.RESULTS: Individuals with mild intellectual disability had a higher risk of any substance use-related problem compared to the general population (HR, 1.81; 95% CI, 1.72-1.91), both in males (HR, 1.76; 95% CI, 1.65-1.89) and females (HR, 1.89; 95% CI, 1.74-2.05). The risks of substance use-related problems were particularly elevated among individuals with mild intellectual disability and psychiatric comorbidities (HR, 2.21-8.24). The associations were attenuated in the sibling comparison models.CONCLUSIONS: Individuals with mild intellectual disability, especially those with psychiatric comorbidity, are at an elevated risk of substance use-related problems. Familial factors shared by full siblings contribute considerably to the association between mild intellectual disability and substance use-related problems.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Beroendelära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Substance Abuse (hsv//eng)
- SAMHÄLLSVETENSKAP -- Sociologi -- Socialt arbete (hsv//swe)
- SOCIAL SCIENCES -- Sociology -- Social Work (hsv//eng)
Nyckelord
- Alcohol abuse
- criminality
- drug abuse
- intellectual disability
- substance use
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Påhlsson-Notini, ...
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Liu, Shengxin
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Tideman, Magnus, ...
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Latvala, Antti
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Serlachius, Eva
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Larsson, Henrik, ...
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Hirvikoski, Tatj ...
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Taylor, Mark J.
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Kuja-Halkola, Ra ...
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Lichtenstein, Pa ...
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Butwicka, Agnies ...
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Hälsovetenskap
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och Folkhälsovetensk ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Hälsovetenskap
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och Beroendelära
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- SAMHÄLLSVETENSKAP
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SAMHÄLLSVETENSKA ...
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och Sociologi
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och Socialt arbete
- Artiklar i publikationen
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JCPP Advances
- Av lärosätet
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Örebro universitet
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Högskolan i Halmstad
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Karolinska Institutet