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- Josefson, AnnaÖrebro universitet,Hälsoakademin (författare)
Nickel allergy as risk factor for hand eczema : a population-based study
- Artikel/kapitelEngelska2009
Förlag, utgivningsår, omfång ...
- Oxford University Press (OUP),2009
- printrdacarrier
Nummerbeteckningar
- LIBRIS-ID:oai:DiVA.org:oru-11994
- https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-11994URI
- https://doi.org/10.1111/j.1365-2133.2008.09006.xDOI
- http://kipublications.ki.se/Default.aspx?queryparsed=id:118456110URI
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- Språk:engelska
- Sammanfattning på:engelska
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- BACKGROUND: In population-based studies using self-reported nickel allergy, a hand eczema prevalence of 30-43% has been reported in individuals with nickel allergy. In a previous Swedish study, 958 schoolgirls were patch tested for nickel. In a questionnaire follow up 20 years later no association was found between nickel allergy and hand eczema. OBJECTIVES: To investigate further the relation between nickel allergy and hand eczema. METHODS: Three hundred and sixty-nine women, still living in the same geographical area, now aged 30-40 years, were patch tested and clinically investigated regarding hand eczema. RESULTS: Patch testing showed 30.1% nickel-positive individuals. The adjusted prevalence proportion ratio (PPR) for hand eczema after age 15 years in relation to nickel patch test results was 1.03 (95% confidence interval, CI 0.71-1.50). A history of childhood eczema was reported by 35.9%, and the PPR for hand eczema in relation to childhood eczema was 3.68 (95% CI 2.45-5.54). When analysing the relation separately in women with and without a history of childhood eczema a statistical interaction was found. The hand eczema risk was doubled in nickel-positive women without a history of childhood eczema, with a PPR of 2.23 (95% CI 1.10-4.49) for hand eczema after age 15 years. CONCLUSIONS: A doubled risk for hand eczema was found in nickel-positive women without a history of childhood eczema. When analysing all participants, there was no statistically significant difference between nickel-positive and nickel-negative women regarding occurrence of hand eczema. The most important risk factor for hand eczema was childhood eczema. The risk for hand eczema in nickel-positive women may previously have been overestimated.
Ämnesord och genrebeteckningar
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Dermatologi och venereologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Dermatology and Venereal Diseases hsv//eng
- MEDICINE
- MEDICIN
- Dermatology and venerology
- Dermatologi och venerologi
- Medicine
- Medicin
Biuppslag (personer, institutioner, konferenser, titlar ...)
- Färm, Gunilla (författare)
- Magnuson, A. (författare)
- Meding, BirgittaKarolinska Institutet (författare)
- Örebro universitetHälsoakademin (creator_code:org_t)
Sammanhörande titlar
- Ingår i:British Journal of Dermatology: Oxford University Press (OUP)160:4, s. 828-8340007-09631365-2133
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