Sökning: onr:"swepub:oai:DiVA.org:oru-15386" >
Effects of cricoid ...
-
Ahlstrand, Rebecca,1973-Örebro universitet,Hälsoakademin,Department of Anesthesiology and Intensive Care
(författare)
Effects of cricoid pressure and remifentanil on the esophageal sphincters using high-resolution solid-state manometry
- Artikel/kapitelEngelska2011
Förlag, utgivningsår, omfång ...
-
2011-01-13
-
Wiley-Blackwell,2011
-
printrdacarrier
Nummerbeteckningar
-
LIBRIS-ID:oai:DiVA.org:oru-15386
-
https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-15386URI
-
https://doi.org/10.1111/j.1399-6576.2010.02367.xDOI
Kompletterande språkuppgifter
-
Språk:engelska
-
Sammanfattning på:engelska
Ingår i deldatabas
Klassifikation
-
Ämneskategori:ref swepub-contenttype
-
Ämneskategori:art swepub-publicationtype
Anmärkningar
-
BACKGROUND: Cricoid pressure has been shown to decrease the pressure in the lower esophageal sphincter (LES), increasing the risk of aspiration. Whether this reaction is due to pain associated with the application of cricoid pressure has not been studied. The aim of this study was to compare the effects of cricoid pressure with those of peripheral pain on pressures in the LES, and to study whether remifentanil influences these effects. Data from the upper esophageal sphincter (UES) are also described.METHODS: Continuous solid-state manometry was performed in 14 healthy volunteers. Initially, the effect of remifentanil (target-controlled infusion with a plasma target concentration of 5.0 ng/ml) was studied, and thereafter, the effects of cricoid pressure and peripheral pain stimulation (cold stimulation). Finally, these two interventions were repeated under ongoing remifentanil infusion.RESULTS: Remifentanil decreased the LES pressure significantly [ΔP-6.5 mmHg, 95% confidence interval (95% CI) -1.7 to -11.2]. Cricoid pressure application decreased the LES pressure significantly (ΔP-3.7 mmHg, 95% CI -1.4 to 6.1), whereas peripheral pain did not (ΔP 1.2 mmHg, 95% CI -3.5 to 1.1). Under ongoing remifentanil infusion, no cricoid pressure-induced LES relaxation was observed. Cricoid pressure induced high pressures in the area of the UES, 215.7 (±91.2) mmHg without remifentanil vs. 219.4 (±74.2) mmHg with remifentanil.CONCLUSIONS: Remifentanil as well as cricoid pressure per se induced decreases in LES pressure. However, cricoid pressure-induced changes of the barrier pressure were not significant whether induced with or without an infusion of remifentanil.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
-
Savilampi, Johanna,1977-Department of Anesthesiology and Intensive Care, Örebro University Hospital, Örebro, Sweden(Swepub:oru)jsi
(författare)
-
Thörn, Sven-Egron,1954-Department of Anesthesiology and Intensive Care, Örebro University Hospital, Örebro, Sweden(Swepub:oru)stn
(författare)
-
Wattwil, Magnus,1944-Department of Anesthesiology and Intensive Care, Örebro University Hospital, Örebro, Sweden(Swepub:oru)mswl
(författare)
-
Örebro universitetHälsoakademin
(creator_code:org_t)
Sammanhörande titlar
-
Ingår i:Acta Anaesthesiologica Scandinavica: Wiley-Blackwell55:2, s. 209-2150001-51721399-6576
Internetlänk
Hitta via bibliotek
Till lärosätets databas