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Heavy silicone oil ...
Heavy silicone oil versus standard silicone oil in as vitreous tamponade in inferior PVR (HSO Study) : interim analysis
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- Joussen, Antonia M (författare)
- Department of Ophthalmology, Charité, University Medicine, Berlin, Germany
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- Rizzo, Stanislao (författare)
- U.O.Chirurgia Oftalmica, Azienda Ospedaliero, Universitaria Pisana, Pisa, Italy
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- Kirchhof, Bernd (författare)
- Department of Vitreoretinal Surgery, University of Cologne, Cologne, Germany
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- Schrage, Norbert (författare)
- Augenklinik Kön-Merheim, Cologne, Germany
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- Li, Xiaoxin (författare)
- Beijing University, Beijing, China
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- Lente, Christina (författare)
- Department of Medical Statistics, Rheinisch-Westfälische Technische Hochschule, Aachen, Germany
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- Hilgers, Ralf-Dieter (författare)
- Department of Medical Statistics, Rheinisch-Westfälische Technische Hochschule, Aachen, Germany
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- Crafoord, Sven, 1950- (författare)
- Örebro universitet,Institutionen för läkarutbildning
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Department of Ophthalmology, Charité, University Medicine, Berlin, Germany UO.Chirurgia Oftalmica, Azienda Ospedaliero, Universitaria Pisana, Pisa, Italy (creator_code:org_t)
- 2011-04-07
- 2011
- Engelska.
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Ingår i: Acta Ophthalmologica. - : Wiley. - 1755-375X .- 1755-3768. ; 89:6, s. e483-e489
- Relaterad länk:
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https://onlinelibrar...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- PURPOSE: The Heavy Silicone Oil versus Standard Silicone Oil Study (HSO study) is designed to answer the question whether a heavier-than-water tamponade improves the prognosis of eyes with proliferative vitreoretinopathy (PVR) of the lower retina.METHODS: The HSO Study is a multicentre, randomized, prospective, controlled clinical trial stratified by surgeon comparing two endotamponades within a two-arm parallel-group design. Patients with inferiorly and posteriorly located PVR grade C-A6 were randomized to either HSO or standard silicone oil as a tamponading agent. The main end-point criteria are complete retinal attachment at 12 months and change in visual acuity (VA) 12 months postoperatively compared to the preoperative VA.RESULTS: Forty-six patients treated with HSO were compared to 47 patients treated with standard silicone oil. There was no difference among the groups regarding baseline data. Three patients in the HSO and five patients in the standard silicone oil group fulfilled intraoperative exclusion criteria. There was no significant difference between both groups regarding anatomical success. Neither noninferiority nor superiority was shown with regard to final acuity.CONCLUSIONS: The HSO Study is the first randomized prospective clinical trial to compare heavy and standard silicone oil in patients with PVR of the lower retina. The intermediate results failed to demonstrate superiority of a heavy tamponade.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Oftalmologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Ophthalmology (hsv//eng)
Nyckelord
- heavy silicone oil; PVR; randomized clinical trial; retina; silicone oil
- Medicine
- Medicin
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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